产品名称 Anti-cleaved C-terminal GSDMD抗体[EPR20885-203] 品牌 艾博抗Abcam 货号 ab227821 描述 兔单克隆抗体[EPR20885-203] to cleaved C-terminal GSDMD 经测试应用 适用于: WB不适用于: IHC-P 种属反应性 与反应: Human 免疫原 Synthetic peptide. This information is proprietary to Abcam and...
a, b, Preparation of the GSDMA3(N + C) used for conjugation onto the nanoparticle. Purified GSDMA3 containing a engineered PPase cleavage site between the gasdermin N and C domain was cleaved in vitro to obtain GSDMA3(N + C). a, Coomassie blue staining of the prepared GSDMA3 proteins....
GSDMC 1-4, GSDMD, GSDME, and DFNB59 (official name known as PJVK) in mouse37. The GSDMs are normally self-inhibited through the intramolecular association between the N-terminal pore-forming domain and the C-terminal
In the band picture, the protein symbol ASC is apoptosis-associated speck-like protein containing a caspase-recruitment domain, NLRP3 is Nod-like receptor protein-3, CASP1 is caspase-1, CASP11 is caspase-11, GSDMD-FL is full-length gasdermin D, and GSDMD-N is N-terminal cleaved from ...
Pyroptosis-related proteins (NLRP3, GSDMD, cleaved caspase-1 and IL-1β) were markedly highly expressed in the liver cirrhosis model ((G,J), *** p < 0.001 vs. the control). The disulfram inhibited the expression of pyroptosis-related proteins, as shown in (H). The expression levels ...