In Vivo: A single injection of rituximab or the murine anti-CD20 Ab 1F5, given i.p. 1 day after the tumor, cures 100% of the animals. Depletion of either NK cells or neutrophils or both in tumor-injected animals does not affect the therapeutic activity of the drug. Similarly, rituximab...
重组抗CD20人源化单抗 (上海医药集团): 一种CD20抑制剂、ADCC、CD20定向的溶细胞作用药物,由Shanghai Pharmaceuticals Holding Co., Ltd. (上海医药集团股份有限公司)公司最早进行研发,目前全球最高研发状态为临床2/3期,作用机制: CD20抑制剂(B淋巴细胞抗原CD20抑制剂),A
Anti-CD20 Therapy Reliance on Antibody-Dependent Cellular Phagocytosis Affects Combination Drug ChoiceThe efficacy of many therapeutic unconjugated monoclonal antibodies (mAbs), including those targeting CD20 in CLL, requires immune cell-mediated cytotoxicity. mAbs have often been optimized for natural killer...
In Vivo:A single injection of rituximab or the murine anti-CD20 Ab 1F5, given i.p. 1 day after the tumor, cures 100% of the animals. Depletion of either NK cells or neutrophils or both in tumor-injected animals does not affect the therapeutic activity of the drug. Similarly, rituximab...
维妥组单抗,Veltuzumab,anti-CD20 antibody 抗体 询价 维多组单抗,Vedolizumab,anti-α4β7 antibody 抗体 询价 Research Grade Gavilimomab (DHE14003) 询价 莫维组单抗,Motavizumab,anti-RSV antibody 抗体相关厂家报价 产品名称价格公司名称报价日期
STING (stimulator of interferon genes) has become a focal point in immunology research and drug discovery [1, 2]. In a healthy individual, STING functions as a signaling hub, orchestrating immune responses to pathogenic, tumoral, or self-DNA detected in the cytoplasm [2]. Upon activation, STI...
Title: “Two Norwegian Researchers Discover Drug Against ME/CFS | Raising Awareness for ME/CFS” http://raisingawarenessfo... Publication: European Society for ME Research and Knowledge Title: “Clinical impact of B-cell depletion with the anti-CD20 antibody rituximab in chronic fatigue syndrome:...
Several antibody products have received marketing authorization for the treatment of hematological malignancies, including against CD20, CD38, and CD52. The approval of brentuximab vedotin (an antibody–drug conjugate against CD30) for the treatment of certain forms of Hodgkin's lymphoma and anaplastic...
Drug Metab Dispos. (2007); 35(1): 86-94. Dong, et al., “B7-H1 pathway and its role in the evasion of tumor immunity.” Journal of Molecular Medicine (2003); 81(5): 281-287. Dong, et al., “Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune...
drug sensitivity, metabolic/idiopathic, Wilson's disease, hemachromatosis, alpha-1-antitrypsin deficiency, diabetic retinopathy, hashimoto's thyroiditis, osteoporosis, hypothalamic-pituitary-adrenal axis evaluation, primary biliary cirrhosis, thyroiditis, encephalomyelitis, cachexia, cystic fibrosis, neonatal chro...