caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Caspase-9 is ubiquitously expressed with highest expression in the heart. Mutations in the CASP9 gene may result in cerebral hypoxia and cervical cancer. STJ90011 was affinity-purified from ...
Gene Ther 12, 320-329.Song W, Sun Q, Dong Z, Spencer DM, Nunez G, Nor JE. Antiangiogenic gene therapy: disruption of neovascular networks mediated by inducible caspase-9 delivered with a tran- scriptionally targeted adenoviral vector. Gene Ther 2005; 12:320-9....
Product nameAnti-Cleaved-Caspase-9 (D330) antibody[STJ90012] Short DescriptionRabbit polyclonal against Cleaved-Caspase-9 (D330) DescriptionRabbit polyclonal to Cleaved-Caspase-9 (D330). ApplicationsELISA, IHC, WB Dilution rangeWB 1:500-1:2000 ...
7). Similarly the Caspase-9 gene expression was not observed in all the control samples, but the expression increased in treated groups i.e. NE mix (10 and 20 µg), Tamoxifen 20 µg and NE mix 10 µg – Tamoxifen 20 µg and the enhanced efficiency appeared to be dose ...
(HSV-tk), inducible caspase 9 (iCasp9), and truncated epithelial growth factor receptor (tEGFR), which can enable CAR T cell elimination53. At present, there are 11 active phase I/II clinical trials of anti-MUC1-CAR T cells against multiple cancer models, some of which are combined ...
抗体名:TMS1; Apoptosis associated speck like protein containing a CARD; Apoptosis-associated speck-like protein containing a CARD; ASC_HUMAN; CARD 5; CARD5; Caspase recruitment domain containing protein 5; Caspase recruitment domain protein 5; Caspase recruitment domain-containing protein 5; hASC; ...
英文名称Caspase-3 中文名称活化半胱胺酸蛋白酶蛋白-3抗体 别名Caspase-3 subunit p17; cleaved Caspase 3; cleaved Caspase-3; APOPAIN; CASP3; Caspase 3 apoptosis related cysteine protease; Caspase3; CPP32; CPP32B; Cysteine protease CPP32; Human cysteine protease CPP32 isoform alpha mRNA complete cds...
The number of caspase-3/7-positive cells was measured using CellEvent Caspase-3/7 Green Detection Reagent (Invitrogen) according to the manufacturer’s instructions. Reporter assays The NF-κB reporter construct was described previously55. All reporter constructs containing the minimal MYC promoter ...
Tissue Specificity:Isoform 1, isoform 5 and isoform 7 are expressed in a wide variety of tissues. Highest expression in peripheral blood leukocytes, spleen, thymus and liver. Barely detectable in brain, testis and skeletal muscle. Involvement in Disease:Caspase-8 deficiency: Disorder resembling autoi...
Caspase-dependent and caspase-independent cell death pathways in yeast Biochem. Biophys. Res. Commun., 382 (2009), pp. 227-231 Google Scholar [263] J.E. Leadsham, V.N. Kotiadis, D.J. Tarrant, C.W. Gourlay Apoptosis and the yeast actin cytoskeleton Cell Death Differ., 17 (2010), ...