AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface. Phosphorylation of PTPN1 at 'Ser-50' negatively modulates its phosphatase activity preventing dephosphorylation of the insulin receptor and the ...
Immunogen: KLH conjugated Synthesised phosphopeptide derived from human Akt around the phosphorylation site of Thr450. ● Predicted Molecular Weight: 56kDa.Anti-phospho-Akt (Thr450)抗体 Storage: Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles). Application: Anti-phospho...
of phosphatidylinositol 3 kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI3 kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylatesAnti-phospho-AKT1 (Tyr474)抗体targets ...
Target Protein:phospho-AKT (Ser473) IR:Immunogen Range:QF(p-S)YS Clonality:Monoclonal Isotype:IgG Entrez Gene:207 Swiss Prot:O57513 Source:KLH conjugated Synthesised phosphopeptide derived from human AKT around the phosphorylation site of Ser473:QF(p-S)YS Purification:affinity purified by Protein...
Vogt, Phosphorylation by Akt disables the anti-oncogenic activity of YB-1, Oncogene 27 (2008) 1179-1182.Bader AG, Vogt PK. Phosphorylation by Akt disables the anti-oncogenic activity of YB-1. Oncogene 2007; 27:1179-82.Bader AG, Vogt PK. Phosphorylation by Akt disables the anti-oncogenic ...
AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface. Phosphorylation of PTPN1 at 'Ser-50' negatively modulates its phosphatase activity preventing dephosphorylation of the insulin receptor and the ...
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residue 308 and serine residue 473 is required for full activation of the AKT1 protein encoded by this gene. Phosphorylation of additional residues also occurs, for example, in response to insulin growth factor-1 and epidermal growth factor. Protein phosphatases act as negative regulators of AKT ...
and serine residue 473 is required for full activation of the AKT1 protein encoded by this gene. Phosphorylation of additional residues also occurs, for example, in response to insulin growth factor-1 and epidermal growth factor. Protein phosphatases act as negative regulators of AKT proteins by ...
C-AKT PKB 修改 Phosphorylation 纯化方法 Affinity Purfied UniProt编号 P31749 UniProt汇总 FUNCTION: General protein kinase capable of phosphorylating several known proteins. Phosphorylates TBC1D4. Signals downstream of phosphatidylinositol 3-kinase (PI(3)K) to mediate the effects of various growth ...