Information regarding the side effects of anti-aging drugs, approval of the U.S. Food and Drug Administration (FDA) on prescription testosterone treatment, and effect of supplements in improving the attention, cognition and focus of an individual, are discussed....
How to combine five clinically available anti-aging drugs with calorie restriction? Koschei the deathless (a villain in Russian, Polish and Ukrainian fairy tales) was immortal, strong, bony and lean (Figure 1). Was it his passion for the young princess Vassilisa, the Beautiful, who rendered ...
This book describes the nature of aging, age-related disorders, and the molecular principles of emerging strategies for anti-aging interventions, while also discussing the discovery of targets for geroprotective drugs. Although significa... SI Rizvi,Çakatay, Ufuk 被引量: 0发表: 2018年 PGC-1α...
, instead of only when they go to the beach. This leads to "incidental sun exposure," one of the most common causes of skin aging, Baxt added. She also said that there's no "safe" amount of time to be outside in the sun without your skin experiencing its rays' degrading effects....
A measure of cell aging provides a measure of health, disease risk, and our ability to respond to therapeutic drugs. We have known for many years that as a cell ages, its telomeres become shorter. Shorter telomeres are associated with shorter lives, says geneticistRichard Cawthon. ...
Inflammation plays an important role in the development of heart failure (HF) after myocardial infarction (MI). Suppression of post-infarction inflammatory cascade has become a new strategy to delay or block the progression of HF. At present, there are no approved anti-inflammatory drugs used to...
Effective treatment with lower toxicity compared to other drugs may be achieved by using natural products. Ginsenoside, a natural material derived from ginseng, has been studied in cancer treatment due to its anti-tumor effects and low toxicity14. There are more than 100 types of ginsenosides ...
(Berberidaceae), and has been used in China for over 2000 years to enhance Yang Qi, improve cardiovascular and cerebrovascular functions, and regulate immune function. It has anti-osteoporosis, anti-oxidation, anti-tumor, and anti-aging effects [108]. Compounds such as flavonoid glycoside, phenyl...
health-care products or drugs using aged mice. It was found that the NMN administration could extend the life span of mice by ~29%. Aging is the most influential determinant and the greatest known risk factor forneurodegenerative diseasessuch asAlzheimer's disease(AD) andParkinson's disease(PD...
The research conducted so far, just using natural products and existing drugs, has shown unequivocally that small molecules can produce a broad spectrum of anti-degenerative effects. Drug discovery for aging is moving beyond its infancy, and preventative medicine that will revolutionize 21st-century he...