Learn about syn addition and anti addition. Discover examples of syn and anti stereochemistry, and examine how both syn and anti addition can...
Syn addition is the addition of two substituents to the same side (or face) of a double bond or triple bond, resulting in a decrease in bond order but... Learn more about this topic: Focal Length | Definition, Formula & Examples
Syn_and_Anti_additionSyn and Anti additionFace
In addition, overexpres- sion of WT human tau did not affect neither the size nor the number of Aβ plaques (Additional file 3: Fig. S3a, b). However, when the analysis was restricted to female 5xFAD mice, we found a significant difference in Aβ burden between 5xFAD/AAV-tau ...
Several syn-nucleopalladation and anti-nucleopalladation pathways were evaluated computationally. The most favorable pathway proceeds through the anti-addition of deprotonated phenolate anion to 10 (via TS1), requiring a barrier of 18.0 kcal/mol. The competing inner-sphere syn-addition pathway (...
In addition, electron transport through the mitochondrial respiratory chain is an essential requirement for oxidative phosphorylation, and this process is associated with the generation of reactive oxygen species (ROS). In particular, when electrons leak from the respiratory complexes, ROS react with mole...
In addition our finding that rituximab only affects VEGF secretion of the rituximab-sensitive GCB cell lines indicates, for the first time, a relationship between rituximab-induced apoptosis and secretion of this growth factor. Activation of the PI3K/AKT/mTOR pathway, which is observed in the ...
Human cytomegalovirus is the largest human herpesvirus and shares many core features of other herpesviruses such as tightly regulated gene expression during genome replication and latency as well as the establishment of lifelong persistence following infection. In contrast to stereotypic clinical syndromes as...
CSR may be necessary to ensure both humoral and mucosal protection from HIV surge. Indeed, IgG1, IgG2, and IgA isotypes of the 3BNC117 bNAb were found in the sera of treated mice in addition to the IgM isotype (Fig.5aand Supplementary Fig.7A–C). Class switched 3BNC117 antibodies we...
Addition of LFE alone increased fatty acid oxidation sig- nificantly, but the increase was abrogated com - pletely by compound C (Figure 4B). These results show that LFE promotes lipid breakdown in an AMPK-dependent manner. LFE reduces body weight gain and fat mass in HFD-induced obese ...