A protein produced in the blood or tissues in response to the presence of a specific foreign antigen. Antibodies provide immunity against certain microorganisms and toxins by binding with them and often by deactivating them. Also calledimmunoglobulin. ...
Staley EM, Carruba SS, Manning M, Pham HP, Williams LA III, Marques MB, et al. Anti-blood group antibodies in intravenous immunoglobulin may com- plicate interpretation of antibody titers in ABO-incompatible transplantation. Am J Transplant (2016) 16(8):2483-6. doi:10.1111/ajt.13760...
Regardless of the decrease in Rh sensitization as a cause of hemolytic disease of the newborn, antenatal antibody screening must be performed in all patients to detect not only anti-D sensitization, but other less common antibodies capable of provoking hemolytic disease of the newborn. The relativ...
Our aim in this case report was to describe anemia caused by anti-Diego a red blood cell (RBC) antibody in a 3-week-old infant derived during pregnancy to low-frequency Diego a RBC antigen. Pre- and postnatal maternal serum screening for unexpected RBC antibodies and determination of RBC ...
In contrast toantiangiogenicagents that aim to inhibit new tumor vessel formation, vascular-targeting agents attack the existing neovasculature in tumors[59]. The goal of using these kinds of agents is to induce tumor endothelial cellapoptosisand in addition microvessel thrombosis. Antibodies specificall...
Nanobodies are successful new biologics in treating mucosal infectious disease as they recognize conserved epitopes on hypervariable pathogens. Cocktails consisting of multiple nanobodies could provide even broader epitope coverage at a lower cost compared to monoclonal antibodies. Identification of conserved ...
Fig. 2: Polyclonal antibodies to PyTRAP inhibit parasite invasion, traversal, and in vivo infection. Mice were immunized three times with PyTRAP or PyCSP ectodomains. a Immune sera were used to verify binding to Py sporozoites via immunofluorescence. Shown is a representative example of fixed, ...
Lin AH, Nepstad I, Florvaag E, Egaas E, Van Do T. An extended study of seroprevalence of anti-Anisakis simplex IgE antibodies in Norwegian blood donors. Scand J Immunol. 2014;79:61-7. doi:10.1111/sji.12130.Lin AH, Nepstad I, Florvaag E, Egaas E, Van Do T. An extended ...
The presence of TNF-α, IL-1β and IL-6 in the cell supernatant was measured with a rat standard-ELISA kit. The results were calculated based on the absorbance levels of complex cytokine-antibodies, and the units of cytokines were described as pg/ml. Western blotting analysis The animal ...
Encephalitis is a condition with a variety of etiologies, clinical presentations, and degrees of severity. The causes of these disorders include both neuroinfections and autoimmune diseases in which host antibodies are pathologically directed against self-antigens. In autoimmune encephalitis, autoantibodies...