The results indicate that the only recommended anthracycline-containing regimen would be carboplatin plus amrubicin—not the combination of cisplatin, doxorubicin, vincristine, and cyclophosphamide—and that the recommended regimens without anthracycline would be carboplatin plus paclitaxel and cisplatin ...
However, accumulating evidence suggests that in patients requiring treatment, early initiation of an anthracycline-based regimen may achieve better response rates and progression-free survival compared with reserving such options until late in the course of disease. Delivery of myelosuppressive chemotherapy ...
An anthracycline-based regimen was administered to 21 study patients and 23 control patients. FOXC1 expression was significantly associated with a worse DFS (HR 2.62, 95% CI 1.05–6.50,P= 0.038) but presented no correlation with OS (HR 2.53, 95% CI 0.76–8.40,P= 0.131) among these ...
BACKGROUND:The aim of this study was to evaluate the pathologic complete response (pCR) rates and relapse-free survival (RFS) and overall survival (OS) of patients receiving neoadjuvant systemic therapy (NST) with trastuzumab in combination with an anthracycline- or nonanthracycline-based regimen.关...
Their role in predicting the outcome of anthracycline-based adjuvant chemotherapy for breast cancer patients has remained controversial.The present substudy of the Scandinavian Breast Group trial 9401, in which an epirubicin-based regimen (nine courses of tailored and dose-escalated fluorouracil, ...
An anthracycline-based regimen was administered to 21 study patients and 23 control patients. FOXC1 expression was significantly associated with a worse DFS (HR 2.62, 95% CI 1.05–6.50,P= 0.038) but presented no correlation with OS (HR 2.53, 95% CI 0.76–8.40,P= 0.131) among these 44 ...
Here, we provide preclinical evidence that the anti-tumour efficacy of the combination of dasatinib and the anthracycline-based regimen CHOEP is augmented when compared with either chemotherapy or dasatinib as monotherapy. The effect is mediated by the induction of cell cycle perturbations, mitochondrial...
Adam Brufsky, MD, PhD:I forgot, it’s true, you’re going to lose your hair. That doesn’t count. Virginia Kaklamani, MD:This is not the only trial that has shown similar results with T-DM1 in the neoadjuvant setting compared to a taxane-based regimen. Then you look at the cost...
(second examination), between the anthracycline-based regimen and taxane (third examination), and after all chemotherapy and prior to surgery (fourth ... M Kalambo,J Stafford,WT Yang - 《Breast Diseases A Year Book Quarterly》 被引量: 154发表: 2013年 DNA repair signature is associated with ...
(30.2%), followed by FL-3A in 27.3%, FL-1 in 23.1%, and FL-3B in 2.5%. The remaining 16.9% of patients had composite lymphoma. In terms of treatment, 43.8% of patients received an anthracycline-based regimen without rituximab, while 24.5% received anthracycline plus rituxim...