Steven D.Colan, Steven E.Lipshultz, Stephen E.Sallan. (2014) Balancing the oncologic effectiveness versus the cardiotoxicity of anthracycline chemotherapy in childhood cancer. Progress in Pediatric Cardiology /
V. et al. Anthracycline chemotherapy and cardiotoxicity. Cardiovasc. Drugs Ther. 31, 63–75 (2017). Article CAS Google Scholar Gui, C., Mo, X., Gu, Y. C. & Ju, J. Elucidating the sugar tailoring steps in the cytorhodin biosynthetic pathway. Org. Lett. 19, 5617–5620 (2017). ...
Anthracyclines such as doxorubicin, daunorubicin, epirubicin, mitoxantrone and idarubicin are the most commonly used chemotherapy drugs in cancer. They are a known cause of cardiotoxicity (Table 1), with acute or/and subacute effects that can manifest as electrocardiographic changes, ventricular and supr...
Chemotherapy Combination drug therapy Drug Therapy Pharmacotherapy Introduction The great development of cancer therapies has resulted in a significant increase in life expectancy for most cancer types. The population of cancer survivors is growing and this has resulted in a new clinical and research...
Anthracycline chemotherapy and cardiotoxicity. Cardiovasc Drugs Ther. 2017;31(1):63–75. 6. Russell RR, Alexander J, Jain D, Poornima IG, Srivastava AV, Storozynsky E, et al. The role and clinical effectiveness of multimodality imaging in the management of cardiac complications of cancer and...
The notion that anthracycline-related cardiotoxicity may develop long after completing chemotherapy suggests that drugs used to treat clinically evident cardiotoxicity should be used much earlier to protect the heart against subclinical cardiotoxicity. Unfortunately, active cardiac prevention by beta-blockers,...
Cardiac troponin T (CTT) is elevated acutely in animal models of anthracycline cardiotoxicity. We assessed CTT release in children receiving anthracylines using a third generation assay. We measured CTT in 30 children receiving anthracycline chemotherapy. A total of 3 samples were taken from each ...
Cancer patients receiving anthracycline-based chemotherapy are at risk to develop life-threatening chronic cardiotoxicity with the pathophysiological mechanism of action not fully understood. Besides the most common hypothesis that anthracycline-induced congestive heart failure (CHF) is mainly caused by generat...
[22]Gharib, M.I. and Burnett, A.K. (2000) Chemotherapy-Induced Cardiotoxicity: Current Practice and Prospects of Prophylaxis. European Journal of Heart Failure, 4, 235-242. [23]Godoy, L.Y., Fukushige, J., Igarashi, H., Matsuzaki, A. and Ueda, K. (1997) Anthracycline-Induced Cardiot...
D. Yellon1 Anthracycline Chemotherapy and Cardiotoxicity Cardiovascular Drugs Therapy (2017) 31:63-75 [201] G. Minotti. P. Menna. E. Salvatorelli. G. Cairo. L. Gianni. Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacological reviews. ...