Missense variants located to the "molecular brake" in the tyrosine kinase hinge region of platelet-derived growth factor receptor-ß, encoded by PFGFRB, can cause Penttinen-type (Val665Ala) and Penttinen-like (Asn666His) premature ageing syndromes, as well as infantile myofibromatosis (Asn666...
In addition to AnxA2 and AnxA7, other annexins have been linked to membrane transport steps along the biosynthetic/exocytotic route. Here, we highlight only AnxA13 as its expression pattern and function is uniquely cell-type specific. AnxA13, in particular the splice variant AnxA13b, is spe...
Anchorage removal like growth factor removal induces apoptosis. In the present study we have characterized signaling pathways that can prevent this cell death using a highly growth factorâ and anchorage-dependent line of lung fibroblasts (CCL39). After anchorage removal from exponentially grow...
Annexin A1; annexin I (lipocortin I); Annexin I; Annexin-1; ANX1; ANXA1; Calpactin II; Calpactin-2; Chromobindin-9; Lipocortin I; LPC1; LPC1annexin-1; p35; Phospholipase A2 inhibitory protein Product Datasheets Product Datasheet ...
Annexins are grouped under 5 major classes (A-E), the 12 annexins which are commonly found in vertebrates are classified under annexin A family and named as annexins A1-A13 (or ANXA1-ANXA13), leaving A12 not assigned in the official nomenclature. Annexins outside vertebrates are classified...
(such asAnnexin A3inneutrophilsand Annexin A8 in the placenta and skin) or restrictive (such as Annexin A9 in the tongue, Annexin A10 in the stomach and Annexin A13 in the small intestine). The fact that multiple Annexins exist in all higher eukaryotic cell types suggests that they play ...
In mammals, 12 different annexins have been identified, named Annexin A1-A11 and A13 [1,2]. One of the first properties described for annexins was the ability to bind negatively charged phospholipids in the presence of calcium. Subsequently, many additional binding partners and cellular roles ...
Anti-Annexin-13/ANXA13 Rabbit pAb 100 μL ¥1650 加入购物车 GB111272-50 Anti-Annexin-13/ANXA13 Rabbit pAb 50 μL ¥950 加入购物车 GB111334-100 Anti-L1CAM Rabbit pAb 100 μL ¥1650 加入购物车 GB111334-50 Anti-L1CAM Rabbit pAb 50 μL ¥950 加入购物车 GB111414-100 Anti-67kDa...
While most human Anxs, such as AnxA1, AnxA2, AnxA4-7 and AnxA11, are widely expressed, others are more tissue-restricted, like AnxA9 in the tongue, AnxA10 in the stomach and AnxA13 in the small intestine [4]. Anxs typically reside in the cytosol but upon induction of apoptosis, ...
2. The annexin-coated particle according to claim 1, wherein said annexin is any member of the group of annexins, preferably any of annexin A1, annexin A5, and annexin A13, more preferably annexin A1 or annexin A5, and/or is a receptor-binding annexin core domain or a fragment thereof,...