Salcido R,,Popescu A,Ahn C.Animal models in pressure ulcer re-search. Journal of Spinal Cord Medicine . 2007Salcido R, Popescu A, Ahn C. Animal models in pressure ulcer research. J Spinal Cord Med. 2007;30(2):10
We review the pathogenesis of pressure ulcer and the recently reported animal models of pressure ulcer, so as to provide basic experimental basis for further research on the occurrence, development, and prevention of pressure ulcer.压疮是由于长时间的压力、剪切力和摩擦力作用造成的骨骼表面皮肤和皮下...
The animal model deals with the species other than the human, as it can imitate the disease progression, its’ diagnosis as well as a treatment similar to human. Discovery of a drug and/or component, equipment, their toxicological studies, dose, side eff
Ethanol, stress, piroxicam and pylorus ligation-induced gastric ulcer models were used to investigate antiulcer properties. The related mechanisms of action were using the ethanol-gastric lesions protocol. Results In the acute oral toxicity assay, doses of 300 or 2000 mg/kg of estragole ...
Significant reduction (96.47-98.24%) of ulcer size was observed in rats pre-treated with AL (p < 0.001) and CUR (p < 0.001) at all dose levels compared to the untreated control. Their potencies of activity were comparable to the reference drug omeprazole given at a dose of 20 mg/kg ...
travel and trade, the resolution prompted by the SARS experience also urges member states to “ensure collaboration, when appropriate, with veterinary, agricultural and other relevant agencies involved in animal care and research on, and planning and implementation of, preventive and control measures....
(a mixture of parts of 18 Thai medicinal plants: PPF) were investigated in animal models. Anti-cholangiocarcinoma (anti-CCA) was assessed using CCA-xenograft nude mouse model. The antihypertensive, analgesic, anti-inflammatory, antipyretic, and anti-ulcer activities and effects on motor coordination...
in both humans and experimental models have confirmed various bioactivities of 11-keto-β-boswellic acid, such as anti-inflammatory, anticancer, antioxidant, antiulcer and antibacterial effects56. Presently, all these 9 potential bioactive compounds are analyzed for further target prediction in this ...
Particular attention has been paid to the functional characteristics of the cells that facilitate their therapeutic application in large animal models of human disease. In this regard, we describe outcomes of ASCs utilization in translational research with pig and horse models of disease. Furthermore,...
EEZR (125–500 mg/kg) exhibited a significant gastroprotective effect in absolute ethanol, HCl/ethanol, hypothermic-restraint stress, and ischemia/reperfusion-induced gastric lesion models. EEZR (250 and 500 mg/kg) exhibited still a gastroprotective activity in the indomethacin-induced ulcer model....