Model Rulesmeans the State of Oregon’s Attorney General’s model rules of procedure for Public Contracting, which are set forth in OAR Chapter 137, divisions 46, 47, 48, and 49, and required under ORS 279A.065. General Rulesmeans the general rules set out in Part 2 of these QFCA Rul...
While the initial signs of animal abuse begin as early as childhood, many adults overlook the warnings as an “exploratory age of development.” As such, the problem endures because prompt recognition of the signs is essential to stopping the cycle of violence and preventing harm in the future...
(ii) Male and female juveniles and subadults may have different sensitivities to environmental stressors, such as food and diseases. Sex-biased juvenile mortality may reflect sex-specific life histories that affect, for example, the growth and timing of gonad formation44or dispersal patterns28,45,...
Antiretroviral therapy has greatly extended the lifespan of people living with human immunodeficiency virus (PLHIV). As a result, the long-term effects of
abuse, sexual maltreatment, and many more (Bernstein et al.2003; Brown et al.2009; Kaufman and Charney2001; Marangoni et al.2016; Mullen et al.1996). In fact almost two-third of BD patients sustained at least one negative or goal-attainment life event 6 months prior to the index or fi...
There is considerable evidence that high novelty seekers are at increased risk for using drugs of abuse relative to low novelty seekers. This review examin... MT Bardo,RL Donohew,NG Harrington - 《Behavioural Brain Research》 被引量: 1012发表: 1996年 Novelty-Seeking in Rats-Biobehavioral Chara...
Modelling of complex psychiatric disorders, e.g., depression and schizophrenia, in animals is a major challenge, since they are characterized by certain disturbances in functions that are absolutely unique to humans. Furthermore, we still have not identified the genetic and neurobiological mechanisms,...
Post-traumatic stress disorder (PTSD) is defined by the International Classification as impairments to emotional state and reactions to a stressful situation in humans. the symptoms of PTSD include anxiety and intrusive memories of the traumatizing event, nightmares, irritability, increased awareness of ...
1999). Pig models have been used to address lifestyle factors (e.g., stress, drugs, and abuse; Schook et al. 2005), diabetes (Larsen and Rolin 2004), and human brain disorders (Moustgaard et al. 2005; Nielsen et al. 2009). Another important consideration is that pigs are relatively ...
The use of animal models of human disease is critical for furthering our understanding of disease mechanisms, for the discovery of novel targets for treatment, and for translational research. This Special Topic entitled “Animal Models of Human Disease”