Mechanical stress activates angiotensin II type 1 receptor without the involvement of an- giotensin II. Nat Cell Biol. 2004;6:499 -506.Zou Y,Akazawa H,Qin Y, et al.Mechanical st ress activates angiotensin II type 1 receptor wit hout t he involvement of angio2 tensin II. Nature Cell ...
The mechanisms of regulation, activation and signal transduction of the angiotensin II (Ang II) type 1 (AT1) receptor have been studied extensively in the decade after its cloning. The AT1 receptor is a major component of the renin-angiotensin system (RAS). It mediates the classical biological...
These disadvantages are absent with losartan, a selective, orally administered, nonpeptide blocker of the angiotensin II type 1 receptor that recently became available for clinical use. Losartan has a sustained duration of action, permitting once-daily dosing in many patie...
Sirtuin 1 (SIRT1), an NAD+ (nicotinamide adenine dinucleotide)-dependent deacetylase in the proximal tubule, may be involved in renal injury associated with ageing. However, the mechanisms of SIRT1 regulation remain to be elucidated. We recently reported that angiotensin II type 1 receptor (AT1R...
Ab, antibody; AT1R, angiotensin II type 1 receptor; DSA, donor-specific anti-HLA antibody; HLA, human leukocyte antigen. Values are n (%). Data are based on 1845 kidney allograft biopsies performed within the first year after transplantation, in which 299 (16.2%) showed histologic features ...
产品活性:Telmisartan 是一种有效的血管紧张素II 1型受体 (angiotensin II type 1 receptor) 拮抗剂,能够抑制其活性,IC50 值为 9.2 nM。 生物活性:替米沙坦是一种强效、持久的血管紧张素 II 1 型受体 (AT1)拮抗剂,选择性地抑制125I-AngII 与 AT1 受体的结合,IC< 9.2 nM 的 sub>50。 IC50 和目标:IC50:...
产品名称:angiotensin II type1receptor拮抗剂(Telmisartan)英文名称:Telmisartan产品货号:M02773产品规格:1mL(10mM)|50mg|100mg|500mg|1gTelmisartan是一种有效的血管紧张素II1型受体(angiotensin II type1receptor)拮抗剂,能够抑制其活性,IC50值为9.2nM。注:本品仅可用于科研实验,严禁用于临床医疗及其他用途!CAS号:...
产品活性:Telmisartan 是一种有效的血管紧张素II 1型受体 (angiotensin II type 1 receptor) 拮抗剂,能够抑制其活性,IC50 值为 9.2 nM。 生物活性:替米沙坦是一种强效、持久的血管紧张素 II 1 型受体 (AT1) 拮抗剂,选择性地抑制 125I-AngII 与 AT1 受体的结合,IC< 9.2 nM 的 sub>50。 IC50 和目标:IC50...
靶点:Angiotensin II Type 1 Receptor 宿主:Rabbit 用途:WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000 产地:上海 品牌:爱必信(absin) 包装规格:50ug 适应物种:Human 克隆性:Polyclonal 保存条件:Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles ...
上海玉博生物科技有限公司 主要致力于“AT1R(Angiotensin II Type 1 Receptor) 血管紧张素Ⅱ-1型受体抗原 yb-0630P”的生产销售。多年的“AT1R(Angiotensin II Type 1 Receptor) 血管紧张素Ⅱ-1型受体抗原 yb-0630P”生产与销售的经验,与各行业新老用户建立了稳定的