We investigate whether suppressing the activation of the angiotensin II type 1a receptor (AT1a) can ameliorate severe chronic tubulointerstitial damage (TID) after renal ischemia reperfusion (IR) using AT1a knockout homozygous (AT1a) male mice. To induce severe chronic TID after renal IR, ...
Angiotensin II (Ang II) is implicated in the CIH associated increase in MAP. Subfornical organ (SFO), a forebrain circumventricular organ, lacks blood brain barrier and is a major site for the central effects of circulating Ang II. We investigated the effects of Ang II type 1a receptor ...
The mechanisms of regulation, activation and signal transduction of the angiotensin II (Ang II) type 1 (AT1) receptor have been studied extensively in the decade after its cloning. The AT1 receptor is a major component of the renin-angiotensin system (RAS). It mediates the classical biological...
1.人紧张素Ⅱ1A型受体(Type-1A angiotensin II receptor)CLIA试剂盒酶联板(Assay plate ):一块(96孔)。 2. 标准品(Standard):2瓶(冻干品)。 3. 样品稀释液(Sample Diluent):1×20ml/瓶。 4. 生物素标记抗体稀释液(Biotin-antibody Diluent):1×10ml/瓶。 5. 辣根过氧化物酶标记亲和素稀释液 (HRP...
2004. An essential role for angiotensin II type 1a receptor in pregnancy-associated hypertension with intrauterine growth retardation. FASEB J. 18:388-390.Saito T, Ishida J, Takimoto-Ohnishi E, et al. An essential role for angiotensin II type 1a receptor in pregnancy-associated hypertension with...
Hyperplastic vascular smooth muscle cells of the intrarenal arteries in angiotensin II type 1a receptor null mutant mice. Background Angiotensin II (Ang II), which contracts vascular smooth muscle cells (VSMCs), has been reported to regulate VSMC growth. Recently formed transgenic mice without ...
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Inagami, "Type 1 angiotensin II receptor-associated protein ARAP1 binds and recycles the receptor to the plasma membrane," Biochemical and Biophysical Research Communications, vol. 310, no. 4, pp. 1254-1265, 2003.Guo DF, Chenier I, Tardif V, Orlov SN, Inagami T. Type 1 angiotensin II ...
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上海玉博生物科技有限公司 主要致力于“AT1R(Angiotensin II Type 1 Receptor) 血管紧张素Ⅱ-1型受体抗原 yb-0630P”的生产销售。多年的“AT1R(Angiotensin II Type 1 Receptor) 血管紧张素Ⅱ-1型受体抗原 yb-0630P”生产与销售的经验,与各行业新老用户建立了稳定的