ACTIVITY : Neuroprotective; Nootropic; Antiparkinsonian; Anticonvulsant. MECHANISM OF ACTION : Angiotensin II-receptor agonist.MEFFERT SIMONE DR
Comparation of The Effects of Losartan, Captopril, Angiotensin II Type 2 Receptor Agonist Compound 21 and MAS Receptor Agonist AVE 0991 on Myocardial Ischemia‐Reperfusion Necrosis in RatsAVE 0991Compound 21CaptoprilLosartanMyocardial ischemia‐reperfusion injury...
It is known that stimulation of the angiotensin II type 2 (AT2) receptor protects against ischemic brain injury. We recently demonstrated that AT2 receptor stimulation by compound 21 (C21), a direct AT2 receptor agonist, inhibited vascular intimal proliferation with activation of peroxisome ...
Starting at 7 weeks of age, rats were treated with or without compound 21 (0.3 mg/kg/day, n = 16), an AT2 receptor agonist. Metabolics and structural parameters were measured. BP, transverse cardiomyocyte and intersticial fibrose was higher in animals fed with high salt diet compared with...
AT2 receptorIschemic strokeMCAOOxygen–glucose deprivation and VEGF•This study indicate that cerebral VEGF levels could have an effect in the ability to recovery after MCAO-induced damage.•The administration of a non-peptide AT2R agonist (C21) after pMCAO accelerated the neurological recovery ...
[OP.7C.05] ANGIOTENSIN AT2 RECEPTOR AGONIST, COMPOUND 21, PREVENTS ABDOMINAL AORTIC ANEURYSM PROGRESSION AND THE DECREASE OF AORTIC WALL DISTENSIBILITY IN THE RATWe investigated the effects of treatment with the angiotensin II type 1 receptor antagonist, telmisartan, on abdominal aortic aneurysm...
Angiotensin II 5-valine is an agonist of angiotensin receptor. 公司简介 武汉科斯坦生物科技有限公司是一家致力于前沿生物技术研发与成果转化的创新型高科技企业。 公司成立以来,一直专注于生命科学研发与技术服务领域,与 高校建立合作关系,逐步建立并完善了“分离纯化平台”、“分析检测平台”、“代谢组学平台”、“...
Therapeutic window of globular adiponectin against cerebral ischemia in diabetic mice: the role of dynamic alteration of adiponectin/adiponectin receptor expression. Sci Rep. 2015;5:17310. 11. Okada-Iwabu M, Yamauchi T, Iwabu M, et al. A small-molecule AdipoR agonist for type 2 diabetes and...
Angiotensin AT2 receptor agonist ... Hussain,Patel,Ali - 《Journal of Hypertension》 被引量: 27发表: 2015年 Angiotensin AT2 Receptor Agonist Prevents Salt‐Sensitive Hypertension in Obese Zucker Rats Ali Q, Patel S, Hussain T. Angiotensin AT2 receptor agonist prevents salt- sensitive hypertension ...
血管紧张素Ⅱ的2型受体 例句>> 5) angiotensin Ⅱ receptor 血管紧张素Ⅱ受体 1. Expression and biological significance of angiotensin Ⅱ receptors in human meningioma; 血管紧张素Ⅱ受体在人脑膜瘤中的表达和意义 2. Differences of Angiotensin Ⅱ receptor expression between systemic and pulmonary circulatio...