angiotensin II type 2 receptor agonistC21heterodimerhypertrophyinflammationMarfan's syndromenatriuresisneuroprotectionvasorelaxationIntroduction: Angiotensin II, the active endproduct of the renin–angiotensin system (RAS), exerts its effects via angiotensin II type 1 and type 2 (AT1, AT2) receptors. AT1 ...
The angiotensin II type 2 receptor (AT2R) agonist CGP42112A reduces NF-κB p65 DNA binding activity in rheumatoid arthritis fibroblast-like synoviocytes (RA-FLS). NF-κB p65 DNA binding activity in RA-FLS at baseline and after treatment with AT2R agonist was determined by a NF-κB EZ-TFA...
In fact, the direct AT2R agonist, C21, has been shown to support cognitive function in various animal models [15,[17], [18], [19],25,27]. However, little is known about its effects on PSCI. The purpose of this investigation was to determine the impact of chronic AT2 receptor ...
2) AngiotensinⅡreceptors type 2 血管紧张素Ⅱ受体2型3) angiotensin Ⅱ type 2 agonist 血管紧张素Ⅱ受体2型激动剂4) angiotensin Ⅱ type 2 receptors 血管紧张素Ⅱ的2型受体 例句>> 5) angiotensin Ⅱ receptor 血管紧张素Ⅱ受体 1. Expression and biological significance of angiotensin Ⅱ receptors...
[OP.7C.05] ANGIOTENSIN AT2 RECEPTOR AGONIST, COMPOUND 21, PREVENTS ABDOMINAL AORTIC ANEURYSM PROGRESSION AND THE DECREASE OF AORTIC WALL DISTENSIBILITY IN THE RATWe investigated the effects of treatment with the angiotensin II type 1 receptor antagonist, telmisartan, on abdominal aortic aneurysm...
Angiotensin Type 2 Receptor Agonist C21 Ameliorates the High-Fat Diet-Induced Pancreatic β-Cell Dysfunction Partially by Activation of Antiapoptosis and A... We aim to investigate whether C21, a selective angiotensin type 2 receptor agonist, can exert protective effects on pancreatic 尾-cells throug...
A conserved NPLFY sequence contributes to agonist binding and signal transduction but is not an internalization signal for the type 1 angiotensin II receptor. J Biol Chem 1995; 270:16602–9. Article CAS PubMed Google Scholar Hall RA, Richard TP, Lefkowitz RJ . Heptahelical receptor signaling:...
Agonist-induced Phosphorylation of the Angiotensin II (AT1A) Receptor Requires Generation of a Conformation That Is Distinct from the Inositol Phosphate-si... Agonist-induced phosphorylation of the angiotensin II (AT1A) receptor requires generation of a conformation that is distinct from the inositol ...
别名: CGP42112, CGP42112A, Angiotensin AT2 Receptor Agonist 分子式: C52H69N13O11分子量: 1052.2CAS#: 127060-75-7合成方法: Synthetic存储条件: -20 °C,避光,干燥应用: Cardiovascular System & Diseases产品描述: Angiotensin II Receptor Ligand别名CGP42112, CGP42112A, Angiotensin AT2 ...
Angiotensin type 2 receptor agonist compound 21 reduces vascular injury and myocardial fibrosis in stroke-prone spontaneously hypertensive rats. Hypertension 2012; 59: 291–299. Article CAS Google Scholar Carey RM, Howell NL, Jin XH, Siragy HM . Angiotensin type 2 receptor-mediated hypotension in...