Angiopep-2 作为靶头与 CPPs 相结合可获得更好的治疗效果,是由于 angiopep-2 对 BBB 和肿瘤组织上的受体选择性高,但穿透性低;CPPs 恰好相反,CPPs 对 BBB 和肿瘤组织上的受体选择性低,但其穿透性高,从而达到互补的作用,使药物更快、更准地到达靶部位。Jiao 等 [44] 开发了一种基因传递系统,以增强...
利用Design-Expert 8.0.6.1软件,根据表2所得试验数据分别将影响因素与包封率进行多元2次项 拟合,得到拟合方程为Y=51.551 10-8.217 05X1-2.474 10X2+36.102 80X3+0.104 55X1X2+1.140 91X1X3+1.542 00X2X3-0.125 00X12-0.270 20X22-6.116 80X32...
NPs, (Angiopep-2 modified nanoparticles)ANPs, INPs and AINPs negatively stained with 2% sodium phosphotungstate solution, were observed under TEM. NPs were found to be of uniform size and well-formed spherical shape with compact structure (Fig.1). The particle size and zeta potential of...
自组装肽RADA16/TRSAW修饰HA/β-TCP支架 小编zhn2021.03.22