ISAT remains the most influential trial comparing clipping versus coiling of ruptured aneurysms. Only cases that fulfilled the condition of clinical equipoise were enrolled. In other words, only patients who were considered adequate candidates for clipping and for coiling were randomized. The initial ...
But by the third year, resultspublished intheJournal of Neurosurgeryin 2013, showed that the difference had disappeared, and although there was a 5.8% absolute difference with coiling vs clipping, the difference was not significant.
(2005) International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusion. Lancet 366: 809-817 A ...
To compare endovascular coiling with neurosurgical clipping of ruptured basilar bifurcation aneurysms.Patient and aneurysm characteristics, procedural complications, and clinical and anatomical results were compared retrospectively in 44 coiled patients and 44 patients treated by clipping. The odds ratios for ...
The International Subarachnoid Aneurysm Trial II: comparison of clipping vs coiling: key questions. Are the results of the study generalizable? Should clipping be done for patients less than 40 years of age? Surg Neurol. 2008;70:104–7. CrossRef Bebawy JF, Gupta DK, Bendok BR, et al. ...
Background and purpose: Endovascular coiling is an alternative to surgical clipping for ruptured intracranial aneurysms. However, no large multicenter prospective study has compared coiling and clipping in patients with poor-grade ruptured aneurysms. We aimed to determine differences in postoperative complica...
Surgery (clipping) vs embolization (coiling) Surgery has been the conventional method of aneurysm treatment. Surgery entails direct exposure of the aneurysm, the parent vessel(s) and surrounding structures. The aneurysm is then secured by the placement of a metallic clip along the neck thereby excl...
Endovascular coiling has emerged as a less invasive alternative to conventional surgical clipping to treat aneurysms. Patients and methods This study was done prospectively in the Cairo University (Kasr El-Eini) hospitals to evaluate the outcome of both modalities used in the treatment of ruptured ...
Clipping resulted in significantly greater disability in the short term (≤6 m)(OR on the Glasgow Outcome Scale, 2.72; 95% CI, 1.16–6.34), but not in the long term (6 m)(OR for Glasgow Outcome Scale, 2.12; 95% CI, 0.93–4.84)./p pConclusions/p pCoiling was a better procedure ...
Endovascular techniques can be divided into: parent artery reconstruction with coil deposition (primary coil, balloon-assisted coiling, stent-assisted coiling, and other new techniques such as neck reconstruction devices and intraluminal occlusion devices); reconstruction with flow diversion; and deconstructi...