Besides estrogen and progestogens, androgens have also been suggested to affect the biological function of the female reproductive tract. We investigated the distribution and intensity of immuno-cytochemical estrogen receptor (ER), progesterone receptor (PR) and androgen receptor (AR) staining in the ...
[translate] aGlucocorticoid receptor , androgen receptor , progesterone receptor , estrogen receptor 糖皮质激素的感受器官,雄激素感受器官,孕酮感受器官,女性荷尔蒙感受器官[translate]
The three main sex steroid receptors, estrogen, progesterone, and androgen, have not been sufficiently studied in airway smooth muscle cells (ASMC), and the sex hormone regulation on these receptors is unknown. We examined the presence and regulation of sex hormone receptors in female and male ...
(3β-diol), a possible endogenous ligand for theestrogen receptor β[69,70]. Finally, there was increased expression ofUDPglycosyltransferase2, B15 (UGT2B15), which in conjunction withUGT2B17mediates theglucuronidationof DHT metabolites. This increase in genes mediating DHT catabolism (AKR1C2,AK...
Sex steroids, such as estrogens and androgens, are important regulators of the humoral immune response. Studies in female mice have demonstrated that alteration of circulating estrogen concentration regulates antibody-mediated immunity. As males have nor
Evaluation of androgen receptor in relation to Estrogen Receptor (AR/ER) and Progesterone Receptor (AR/PgR): a new must in breast cancer? J Oncol. 2019;2019:1393505. https://doi.org/10.1155/2019/1393505. Article CAS PubMed PubMed Central Google Scholar Rangel N, Rondon-Lagos M, Anna...
To determine whether a similar increase in mutations was observed with other lineage-specific TFs, we quantified the rate of SNVs at estrogen receptor-binding sites (ERBS) in breast cancer (Supplementary Fig. 3). Similar to what we observed at ARBS in PCa, breast cancer had the highest ...
Androgen receptors are present in mammary epithelial cells in addition to estrogen and progesterone receptors. The proposed mechanisms include either direct stimulation of the androgen receptors or conversion to estradiol by the aromatase enzyme present in breast tissue. Androgens, particularly DHEA and tes...
Because of increased P450 aromatase mRNA expression in the PCOS endometrium [63], our findings do not rule out the possibility that flutamide might affect decidualization and implantation through other mechanisms (e.g., through interactions with estrogen receptor) in vivo [64], and this requires ...
An N/C interaction was also reported for the estrogen (Kraus et al., 1995), progesterone (Tetel et al., 1999) and mineralocorticoid receptors (Pippal et al., 2009), although the interaction motifs were not defined. The androgen-dependent AR N/C interaction is inhibited by the classical ...