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The meaning of ANTIANDROGEN is a substance (such as cyproterone) that tends to inhibit the production, activity, or effects of testosterone and other male sex hormones. How to use antiandrogen in a sentence.
Testosterone, sex hormone-binding globulin, and the development of type 2 diabetes in middle-aged men: prospective results from the Massachusetts male aging study. The objective was to examine prospectively the association between low testosterone and sex hormone-binding globulin (SHBG) levels and the...
M. Isidori, “Testosterone Treatment to Mimic Hormone Physiology in Androgen Replacement Therapy. A View on Testosterone Gel and Other Preparations Available,” Expert Opinion on Biological Therapy, Vol. 7, No. 7, 2007, pp. 1093-1106. doi:10.1517/14712598.7.7.1093...
例句Without male hormone receptors to respond to testosterone, the researchers started to suspect androgen receptors were not the players they had been assumed to be.没有雄激素受体对雄激素发生反应,研究者开始想到雄激素受体并非他们原来想象得那样起作用。
Androgen, any of a group of hormones that primarily influence the growth and development of the male reproductive system. The predominant and most active androgen is testosterone, which is produced by the male testes. The other androgens, which support t
D. Androgen-receptor blockade enhances pulsatile luteinizing hormone production in late pubertal males: evidence for a hypothalamic site of physiologic androgen feedback action. Pediatr. Res. 35, 102–106 (1994). Article CAS Google Scholar Maughan, B. L. & Antonarakis, E. S. Enzalutamide in ...
As previously shown13, male AROM+ mice have significantly higher estradiol and lower testosterone levels compared to wild type (WT) male mice. Furthermore, pharmacological inhibition of the aromatase activity resulted in the anticipated normalization of the hormone levels (Fig. 1A). Thus, the male...
Androgen receptor (AR) belongs to the steroid hormone receptor group of ligand-activated transcription factors in the nuclear receptor superfamily. AR mediates the action of physiological and exogenous androgens to regulate the expression of a network of
Studies on rat and human prostate showed that 5α-DHT, rather than testosterone, might be the active androgenic hormone at the target site (Farnsworth and Brown, 1963;Bruchovsky and Wilson, 1968) and this conversion could also take place in the skin (Wilson and Walker, 1969;Flamigni et al...