A post-marketing trial also evaluated any potential effects of ARIMIDEX on lipid profile. In the primary analysis population for lipids (ARIMIDEX alone), there was no clinically significant change in LDL-C from baseline to 12 months and HDL-C from baseline to 12 months. In secondary population ...
During the ATAC trial, more patients receiving anastrozole were reported to have an elevated serum cholesterol compared to patients receiving tamoxifen (9% versus 3.5%, respectively). A post-marketing trial also evaluated any potential effects of anastrozole on lipid profile. In the primary analysis ...
Similar results are seen for raloxifene, but it has a more favorable side-effect profile. Data on contralateral tumors from women in adjuvant trials treated with aromatase inhibitors suggest that new tumors can be reduced by another 50% with these drugs, suggesting a potential 75% reduction of ...
Wakeling AE, Dukes M, Bowler J: A potent specific pure antiestrogen with clinical potential. Cancer Res 51: 3867-3873, 1991 Robertson JFR, Howell A, Abram P, Lichinitser M, Elledge R: Fulvestrant versus tamoxifen for the first-line treatment of advanced breast cancer (ABC) in postmenopau...
Our Arimidex (anastrozole) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. FDA Drug Information Drug Description Indications & Dosage Side Effects Drug Interactions Warnings & Precautions Overdose & ...
Similar results are seen for raloxifene, but it has a more favorable side-effect profile. Data on contralateral tumors from women in adjuvant trials treated with aromatase inhibitors suggest that new tumors can be reduced by another 50% with these drugs, suggesting a potential 75% reduction of ...
Tau Pathology and Neurochemical Changes Associated with Memory Dysfunction in an Optimised Murine Model of Global Cerebral Ischaemia-A Potential Model for Vascular Dementia? Neurochem. Int. 2018, 118, 134–144. [Google Scholar] [CrossRef] Yague, J.G.; Lavaque, E.; Carretero, J.; Azcoitia,...
If the ETGI value for the combined treatment was lower than that for anastrozole, the observed effect was defined as antagonistic. 3.10.4. Body Weight Change The changes in b.w. were determined to evaluate the potential toxicity of the applied treatment and were calculated using the following ...