Solitary plasmacytoma is the rarest type of plasma cell neoplasm, and the anaplastic form is even more uncommon. Plasmacytoma most commonly originates in bone and predominantly affects older patients. We describe the case of a 35-year-old woman with solitary osseous anaplastic plasmacytoma that ...
52 primary mediastinal B-cell lymphoma, diffuse large B-cell lymphoma, primary effusion lymphoma, adult T-cell leukemia/lymphoma,53 mast cell neoplasm,53 and mycosis fungoides (MF).54 The unique expression pattern OncoTargets and Therapy 2014:7 Powered by TCPDF (www.tcpdf.org) submit your ...
The distinct DNA binding of BATF and BATF3 in ALCL indicated cell-type-specific expression. Indeed,BATFmRNA was largely restricted to, andBATF3was exclusively expressed in ALCL cell lines (Fig.1c, upper left).BATF2was not expressed (data not shown). We confirmed high BATF and BATF3 prot...
CD38 negative anaplastic plasma cell myeloma with (14;16) translocation: a diagnostic dilemma for highly aggressive neoplasm: case reportAnaplastic myelomaCD38 IHC markerst(1416)Anaplastic plasma cell myeloma (PCM) is an aggressive morphological variant of myeloma characterized by involvement of ...
Since the other reports were incongruent with the histopathology report, for establishing a diagnosis of plasmacytoma, Immunohistochemistry of the specimen was done which revealed it to be a case of plasmablastic plasma cell neoplasm favoring plasmablastic lymphoma. The diagnostic confusion which arose ...
Anaplastic Lymphoma Kinase positive Large B-cell Lymphoma (ALK+LBCL), is a rare entity, of which case reports exist in literature. It is a B-cell neoplasm with plasma-cell differentiation and displays plasmablasts/immunoblast like cells along with a peculiar immuno-histochemical profile. The ...
Empirically, these data suggest that BCC has the potential to become an aggressive metastatic neoplasm, given the right immune and stromal environment. Moreover, a functional B lymphocyte system appears to prevent this growth. As human lymphocytes also engraft in SCID-beige mice, the original host...