In this work, we address the topic of within-gene distribution of pathogenic and benign variants, reveal significant clustering of missense changes across the entire coding genome, and use this information to build a positional score. This value is then integrated with other unsupervised independent ...
S1). After extracting the expression matrix of all cells in the tumor tissue and calculating the enrichment scores of hypoxia-related gene sets, we found that there were significant differences in the enrichment scores of the four hypoxia-related gene sets of the five types of cells (Fig. 1B...
The expression of ATF4 was found to be suboptimal and demonstrated a significant correlation with enhanced disease-specific survival (p = 0.012) andoverall survival(p = 0.032) in breast cancer as well as other malignancies. We conducted an analysis to investigate the interaction between the infiltra...
A value of FDR < 0.05 was considered statistically significant [26]. To study the differences in BPs between different subgroups, we performed GSEA based on the gene expression profile dataset of patients with CESC. GSEA is a computational method to analyze whether a specific gene set has ...
Association between a single nucleotide polymorphism of the IL23R gene and tuberculosis in a Chinese Han population: a casecontrol study .#The present study suggests that there is no significant association betweenIL23Rgene polymorphism and tuberculosis susceptibility in the Chinese Han population... J ...
2B’,B”,C’ and C”), demonstrating a significant improvement in image interpretation and quantitative analysis. Regarding RD profiles, we verified that these maps can capture more efficiently protein distribution along the cell cytoplasm, which is not evaluated with IN profiling only (Fig. 2C”...
Background. Chronic cutaneous lupus erythematosus (CCLE) and subacute cutaneous lupus erythematosus (SCLE) are both common variants of cutaneous lupus erythematosus (CLE) that mainly involve the skin...
Variation in the number of SET domain-containing genes among the species used in this study reflects the lineage-specific expansion of the gene family [43]. Further, we observed a significant variation in the number of orthologous SET domain-containing genes between potato and other species used ...
No significant associations with body mass parameters were identi- fied for the additional three common variants identified in the NIH-NICHD group, rs11667582, rs3810327 and rs16980091. We subsequently assessed the association between these four SNPs and HOMA-IR. As shown in Table 3, none of ...
three heptapeptide variants were found: WRKYGKK (CtWRKY25, − 59and − 78) in group IIc, WKKYGEK (CtWRKY24, − 26and − 81) in group IId and WRKYGHK (CtWRKY60) in group III (Fig.S1). Group I included 17CtWRKYmembers, all of which had 2 WRKY conserved domains ...