Also, given that the amount of host DNA present in each sample remains undetermined during sample preparation, it is possible that the number of detected functional features was impacted. These technical limitations are reflective of some of the challenges encountered when conducting metagenome-based ...
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Rights and permissions Reprints and permissions About this article Cite this article Dai, C., Zhang, Z., Shan, G. et al. Advances in sperm analysis: techniques, discoveries and app...
Cox observed that the baseline hazard function in equation (8) could be left unspecified if the effect of a covariate on one individual remains the same for all times T (e.g., if an environmental variable doubles your personal risk of dying at time 5, it also doubles your risk at time...
thereby addressing their connection to a community and to mental health care. Nevertheless, in the US and many other countries, mental health care remains difficult to access, and care coordination was likely included as a component of many interventions due to the complexity of navigating mental ...
However, the association with important safety outcomes, such as infection, remains uncertain. Objective To examine the risk of infection associated with intravenous iron compared with oral iron or no iron. Data Sources Medline, Embase, and Cochrane Central Register of Controlled Trials (CENTRAL) ...
A limitation of the study was that only insurance claims were analyzed. Conclusion: Moderate to severe psoriasis remains persistently untreated or under-treated. We suggest that potential barriers preventing access to care be explored. Funding: This study was sponsored by Pfizer Inc. Keywords: ...
Technical advances have improved the accuracy, speed and efficiency in the analysis of sperm motility, morphology and genetics. Advances in sperm analysis improve sperm selection for infertility treatment by measuring sperm behaviour and biomarkers of fertility potential. Discoveries in sperm locomotion and...
In view of available evidence, genetic testing of ACE I/D polymorphism prior to clinical decision making is not currently justified. The relation between ACE genetic variation and response to treatment in CAD remains an unresolved issue. The results of long-term and properly designed prospective stu...
The assessment of diabetes was judged as low risk of bias in seven, moderate in two studies, and high in one study. Eight studies focused on type 2 diabetes13,28,31,32,33,34,35, one on both types30, and for one it remains unclear which type of diabetes was investigated29. The SRR...
Dental caries and periodontitis account for a vast burden of morbidity and healthcare spending, yet their genetic basis remains largely uncharacterized. Here, we identify self-reported dental disease proxies which have similar underlying genetic contribu