Sampling is done without respect to time or disease status, and, therefore, the design is more flexible than a nested case-control design. Despite the efficiency of the methods, case-cohort designs are not often used because of perceived analytic complexity. In this article, we illustrate ...
A study combining two study designs, the case-cohort design, is a combination of a case-control and cohort design that can be either prospective or retrospective. The case-cohort design can be viewed as a variant of the nested case-control design.7 In a nested case-control study, one star...
and exposure information is to be collected for a case-cohort sample.stratified according to the correlate, and the subcohort is selected by stratified randomsampling.A number of possible methods for the analysis of such exposure stratifiedcase-cohort samples are presented and some of their ...
is born, or to any dated event—a machine is assembled on a particular date. A set of individuals who begin serving a prison term at the same point in time might also define a cohort for certain purposes, in which case “birth” refers to initiation into a particular role ...
In a nested case–control analysis, adjusted odds ratios (ORs) for cancer overall were 1.50 (95% CI 1.30–1.74) for psoriasis of ≥4 years duration and 1.53 (95% CI 0.97–2.43) for patients receiving systemic treatment (marker of disease severity). Lymphohematopoietic malignancy risk was ...
Microbiome-metabolome studies of the human gut have been gaining popularity in recent years, mostly due to accumulating evidence of the interplay between gut microbes, metabolites, and host health. Statistical and machine learning-based methods have been
Background/AimsEvidence of an increased bone fracture risk in coeliac disease is on debate. Our aim was to review systematically the current published information on fractures in coeliac disease and to perform a meta-analysis.MethodsCase–control and cohort designs were identified by searching MEDLINE...
This cohort study evaluates the association of “stand your ground” laws with US homicide and firearm rates nationally and by state.
The flow of participants with inclusion and exclusion criteria for every cohort and this analysis are presented in Fig. 1. A completed case analysis was conducted. Statistical analysis Outcome The outcome variable was the number of incident falls. For SCT and KFPS, this referred to the reported ...
We used the ratio between women and men in the single-study samples as a proxy for sex-specific effects. Sex ratios were heavily skewed towards larger numbers of women in each cohort (median 83% women), and we could not find significant associations between sex ratio and overall (t(62)...