When interpreting ANA test results, doctors typically look at the titer level and the staining pattern under a microscope. A higher titer, such as 1:160 or above, may indicate a greater likelihood of an autoimmune condition, while lower titers, like 1:40, can be found in healthy individuals...
Vogt-Koyanagi-Harada syndrome, and in miscellaneous non-inflammatory diseases, it is not associated with SARD, even when present at very high titer.ConclusionsICAP has clearly provided a common platform to address issues that are of great interest to the ANA community and closely linked to ANA in...
Using the ANA-IIF test on HEp-2 cells results in the detection of high-titer antibodies with a DFS70-like pattern in 1% to 15% of cases in patients referred for ANA testing (Dellavance et al., 2005, Bizzaro et al., 2007, Kang and Lee, 2009, Mahler et al., 2012a, Miyara et al...
Role of the Sponsor: The sponsors provided funding, but had no role in determining study design, data colletion, or interpretation. References 1. Chen SM, Dumler JS, Bakken JS, et al. Identification of a granulocytotropic Ehrlichia species as the etiologic agent of human disease. J Clin Mi...
The present review intends to provide elements allowing the clinician to perform a critical interpretation of results of an ANA-HE-2 test, including analysis of the titer and the fluorescence pattern.doi:10.1590/s0104-42302007000500021A.Dellavance...
Use of Computer-Aided Immunofluorescence Microscopy (CAIFM) for Interpretation of Antinuclear Antibody (ANA) Pattern and Titerantinuclear antibodyautoimmune diseasedigital pathologycomputer-aided immunofluorescence microscopyThe assessment of antinuclear antibodies (ANA) by indirect immunofluorescence (IFA) allows ...
Results Samples are run on NOVA Lite barcoded slides, providing positive patient identification from processing through interpretation. NOVA View results are expressed in LIU, and interpreted as negative or positive based on a pre-set cut-off. The detection limit of the system was established at ...
However, it should be noted that the specificity associated with the 1:80 cut-off titer is low (74.7%) [47]. Using the mentioned dilution, up to 13.3% of heathy individuals show ANA-positive results [27]. The high sensitivity obtained using a cut-off point of 1:80 is the key aspect...
The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results. References Mariz, H.A.; Sato, E.I.; Barbosa, S.H.; Rodrigues, S.H.; Dellavance, A.; ...