底物:Hep-2细胞其阳性滴度>1:20有意义附:各种ANA模型和相关疾病的关系以细胞核蛋白质为靶抗原的ANA荧光染色模型可以是千姿百态,这些模型是不同的核蛋白物质所形成,不同的核型和自身免疫性疾病密切相关:1.均质型(homogeneous pattern,H):此染色型与抗dsDNA抗体、抗组蛋白抗体有关。常出现在SLE病人血清中,特别是SLE...
For example, the nucleolar pattern is more commonly seen in the disease scleroderma, while the homogeneous pattern is often associated with systemic lupus erythematosus (SLE). The ANA speckled pattern, on the other hand, is seen in many conditions including Sjögren's syndrome and mixed ...
Homogeneous:Total nuclear fluorescence due to an antibody directed against DNA or histone proteins. Common insystemic lupus erythematosus. Peripheral:Fluorescence occurs at the edges of the nucleus in a shaggy appearance. Anti-DNA and anti-nuclear envelope antibodies cause this pattern. Seen in systemic...
>1:100)in LN patients were 100%(80/80),42.5%(34/80) LN patients present homogeneous pattern in the sero,which were significantly more than that in SLE patients (21.79%,17/78);While granular pattern in SLE group(73.08%,57/78) was obviously higher than that of LN group(53.75%,43/80...
ANA检测的质量控制 Venus Williams 1980.6.17 185 cm, 75 kg 43 champing titles 597 win / 147 lost Michael Jackson 1958.8.29 -2009.6.25180cm, 60kg 6
1) Anti-dsDNA Antibodies a) Peripheral or homogeneous pattern on routine IFA b) Definitive detection and quantitation is performed on more specific substrates 1. IFA using the hemoflagellate Crithidia luciliae as substrate 2. Very specific for SLE ...
The samples for the ODMR measurements were diluted with degassed glycerol added to a final concentration of 60% (v/v) to obtain homogeneous and transparent matrices upon freezing. The glycerol was added immediately before the insertion into the cryostat to avoid sample degradation [58]. The final...
底物:Hep-2细胞其阳性滴度>1:20有意义附:各种ANA模型和相关疾病的关系以细胞核蛋白质为靶抗原的ANA荧光染色模型可以是千姿百态,这些模型是不同的核蛋白物质所形成,不同的核型和自身免疫性疾病密切相关:1.均质型(homogeneous pattern,H):此染色型与抗dsDNA抗体、抗组蛋白抗体有关。常出现在SLE病人血清中,特别是...
The main ANA staining patterns informed by most of the hospitals include nuclear patterns, such as homogeneous (AC-1), speckled (AC-4, 5), nucleolar (AC-8-10), and centromere (AC-3), together with cytoplasmic reticular/AMA (mitochondria-like) (AC-21). However, the remaining patterns, ...