As already mentioned, the ICH guideline S1B(R1)10 allows for sponsors to substitute the requirement for a second, long-term carcinogenicity study in an additional rodent species (typically a mouse), for short or medium duration animal studies using the initiation/promotion model, or other rodent...
Ecosystem disruptions by the dispersal of domesticated species have had dramatic impacts when released, such as those shown in Table 9.9. The Academy states that: Table 9.9. Factors contributing to level of concern for species transformed Empty CellFactor contributing to concern Empty Cell AnimalNumber...
Their swimming mode could be described as balistiform; although the fins have shorter bases than those of the previous species, their motion is typically undulation rather than oscillation. In this group the cornetfishes, family Fistulariidae, and trumpetfishes, family Aulostomidae, supplement ...
R. et al. Quorum sensing between bacterial species on the skin protects against epidermal injury in atopic dermatitis. Sci. Transl Med. 11, eaat8329 (2019). CAS PubMed PubMed Central Google Scholar Kim, B. E. & Leung, D. Y. Epidermal barrier in atopic dermatitis. Allergy Asthma ...
species. Similar-sized plants (ramets), each consisting of a single tiller with attached roots, were selected and used for this experiment. All the ramets of both species were collected within about 500 m, which should reduce the chance of different genotypes. All selected ramets were about ...
(Kew Science; Ting and Gilbert2000). Furthermore,D. esuclentaandD. bulbiferaare known as ‘Chinese yam’ in some regions, whereas the name ‘cinnamon vine’ typically refers toD. polystachyaTurcz. but is also used for other yam species in the Americas, increasing the degree of confusion (...
Transmission of novel coronavirus (SARS-CoV-2) in humans happens either through airway exposure to respiratory droplets from an infected patient or by touc
while electrolyses would typically result in an unstable product,the patented ECA technology presented here is a process that utilizes and enhances this ECA process by selectively retaining specific species to produce NEW that is highly biocidal,but has a very low chemical load compared to sodium ...
“single-stage” methods, in which species trees are inferred by simultaneously modeling the evolution of sequences among all sampled loci to output a species tree estimate [17–20]. These single-stage model-based methods often have desirable statistical properties, but because they typically ...
Tall fescue (Festuca arundinacea Schreb.) is major cool-season forage and turf grass species worldwide, but high-temperature is a major environmental stress that dramatically threaten forage production and turf management of tall fescue. However, very little is known about the whole-genome molecular...