However, the features underlying the genetic mobility of those integrons have not been studied, except in this A. baumannii strain. In that latter organism, the blaVEB-1-containing integron was associated, at its 3′-extremity, with a sul1-type integron structure containing an ISCR1 element ...
More broadly, knowledge of the spectrum of epistatic relationships is crucial for analyzing the manifestation of quantitative traits, for guiding efforts to tailor drug treatments to an individual’s genetic makeup, and for developing rational strategies for drug-combination therapies. Finally, central ...