An operon is a group of genes that includes an operator and a common promoter region plus one or more structural genes. Transcriptional regulation occurs through inducer or repressor proteins that interact with
16.11). Such polycistronic mRNA is typically found in prokaryotes. The genes in an operon are often related functionally, so it makes good sense to regulate them as a group. For example, an operon may encode several enzymes that take part in the same biochemical pathway. Some operons have ...
In biological terminology, the operon generally represents a group of genetic makeup which works collectively to produce an mRNA (messenger RNA) unit. Such nucleotide sequence is widespread in microorganisms. Its characteristic enables polypeptide production to be coordinated in reaction to the cell's ...
The ars operon consists of a group of genes coding for a transmembrane pump and an arsenate reductase (arsC). The operon includes a regulatory gene (arsR) and a gene coding for an arsenite-specific pump (arsB) as well as arsC [13]. Arsenite is pumped directly out of the cell by the...
It is characterized by its low affinity (Km 7-10 mM), but high Vm [11], thus being able to dissimilate high concentrations of acetate. These two genes belong to the same operon [12] and are constitutively expressed, although ackA is slightly activated by Fnr [13]. The reaction ...
The HrAgo1 operon is also unique in that flanking hrAgo1 are an rnc gene, encoding a protein that comprises an RNaseIII domain fused to a double-stranded RNA binding domain (dsRBD), and a gene encoding a HEDxD/H helicase (Fig. 1c). These domains show homology to the functional ...
Signatures of parallel evolution provide a simple way to identify putative beneficial mutations that underpin adaptation to the novel environment of the human host3,27. Parallel evolution occurred in 3 genes or operons that have functional roles in resistance to carbapenem antibiotics (oprD)27, algina...
The first is the ulaG cistron that encodes the L-ascorbate 6-phosphate lactonase (UlaG) involved in the conversion of L-ascorbate 6-phosphate to L-gulonate 6-phosphate in the catabolism of L-ascorbate [18] (Additional file 2). The second unit comprises the ulaABCDEF operon. Genes ul...
Although bacteria within the Verrucomicrobia phylum are pervasive in soils around the world, they are under-represented in both isolate collections and genomic databases. Here, we describe a single verrucomicrobial group within the class Spartobacteria that is not closely related to any previously desc...
Anoperonis a cluster of genes that are transcribed together to give a single messenger RNA (mRNA) molecule, which therefore encodes multiple proteins (Fig. 16.11). Suchpolycistronic mRNAis typically found in prokaryotes. The genes in an operon are often related functionally, so it makes good se...