Importantly, the deep-learning-based discrimination of putative causal eQTLs displayed good performance for both the distal and proximal regulatory regions (Fig. 2b). Additional evidence for the ability of Huatuo to pinpoint putative causal functional variants came from the identification of pathogenic ...
Another key point for the future is the reconciliation of the macro-anatomical perspective and comparative approach used by researchers interested in encephalization and the much finer techniques used in proximal studies of cognitive processes, which work at the level of single cells, neurotransmitters,...
The classic form of distal desminopathy, due to single heterozygous variants, has an early adult onset with a primary involvement of hand and lower leg muscles. When the disease progresses proximal muscles are frequently involved with a peculiar preference of the semitendinosus muscle on imaging (...
KIM-1 was secreted from proximal renal tubular epithelial cells during the kidney injury caused by ischemia, hypoxia and toxicity, and its level refers to the extent of kidney damage27. Studies in animals have shown that KIM-1 is produced in response to ischemia that may reflect kidney ...
Introduction Julia and Python resources on mathematical epidemiology and epidemiology informed deep learning methods. Most about package information. Main Topics include Data Preprocessing Basic Statistics and Data Visualization Differential Programing and Data Mining such as bayesian inference, deep learning...
The estimation of causal effect requires no unmeasured confounders and inclusion of all confounders without misclassification [19]. UAI in the interval of rectal STI diagnosis is the primary, overriding confounder of the association in that it is the most proximal, direct behavior by which an ...
As the inflorescence of wheat, spike architecture largely determines grain productivity. Dissecting the genetic basis for the spike morphology of wheat can contribute to the designation of ideal spike morphology to improve grain production. The present s
However, at the molecular level, the C locus remain uncharacterized, mainly because of their location in proximal segments of chromosomes regions with reduced levels of recombination. The essential domestication gene Q exists on the long arm of chromosome 5A (5AL), has been studied for decades ...
For the former, they applied the modified SVM to machine fault diagnosis, such as the least square SVM [63,165,186–191], the proximal SVM [192–194], the one-class SVM [195], the hyper-sphere-structured SVM [196], the wavelet SVM [182,189,197–200], the ensemble SVM [201,202]...
3c). To confirm that HNRNPC and PABPC4 act in concert to control the APA of HNRNPC targets, we performed 3′-end RNA-seq comparing HNRNPC/PABPC4 double KD cells with PABPC4 KD alone. Unlike Fig. 2e, in this comparison, we did not observe the significant proximal-to-distal switching ...