Bone tissue engineeringosteoinductiveosteoconductivebone remodellingmacrophagesBone tissue has the capability to regenerate itself; however, defects of a critical size prevent the bone from regenerating and require additional support. To aid regeneration, bone scaffolds created out of autologous or allograft ...
Engineering bone tissue using human dental pulp stem cells and an osteogenic collagen-hydroxyapatite-poly (l-lactide-co-ɛ-caprolactone) scaffold. Rouabhia, "Engineering bone tissue using human dental pulp stem cells and an osteogenic collagen-hydroxyapatite-poly (L-lactide-co-epsilon-caprolac- ...
The core approach of tissue engineering consists of provision of an interactive environment between cells, scaffolds and bioactive molecules to promote tissue repair. To achieve this goal, theex vivoengineered cell-scaffold constructs could be transplanted to the site of injury. Alternatively, the repai...
Bone–tissue engineering, which consists of repair and regeneration, is an area that has generated a lot of interest. The fast pace of development of materials for bone–tissue engineering suggests the potential to be clinically viable sooner than other fields of tissue engineering. Products, such...
The cornea has long been regarded as a site of immune privilege since it was avascular and was thought to lack resident immune cells. Since then, populations of bone marrow-derived leukocytes, which are distinct from stromal keratocytes and include bone marrow-derived cells and macrophages, have...
The natural processes of bone repair are sufficient to restore skeletal integrity for most fractures. However, there are cases of fracture healing in which bone regeneration is impaired or required in large quantities. Recently, tissue engineering has been introduced as a new strategy that uses a ...
To develop a cartilage-like tissue with hybrid scaffolds of demineralized bone matrix gelatin (BMG) and fibrin, rabbit chondrocytes were cultured on hybrid fibrin/BMG scaffolds in vitro. BMG scaffolds were carefully soaked in a chondrocyte–fibrin suspension, which was polymerized by submerging the co...
In bone tissue engineering research, bioreactors designed for replicating the main features of the complex native environment represent powerful investigation tools. Moreover, when equipped with automation, their use allows reducing user intervention and
4.1Introduction Bone tissue regenerationis one of the areas within tissue engineering that has gained considerable attention by the research community (Vacanti and Langer, 1999;Hench and Polak, 2002;Rose and Oreffo, 2002;Gomes and Reis, 2004). Critical size bone defects due to trauma or disease...
Introduction Bone metabolismis characterized by an intimate cooperation of bone cells including osteoblasts,osteoclasts, andosteocytesin order to maintainbone tissuequantity and the integrity of bone structure. In metabolicbone diseasessuch asosteoporosis, bone metabolism is altered, leading tobone lossthat...