Dextroamphetamine sulfate is the dextro isomer of the compoundd,l-amphetamine sulfate and is available as Dexedrine and Dextrostat (Fig. 51-2). These immediate release formulations begin to have an effect within 30 minutes to 1 hour after administration and have duration of action of 4 to 6 ...
Stimulants include drugs such as amphetamine, cocaine, or methylphenidate, which facilitate catecholamine neurotransmission, and methylxanthines (e.g., caffeine, theophylline), which work by interacting with purine receptors. Although compounds like picrotoxin or strychnine have sometimes been called ...
Also, preference for novel objects indicates that the familiar object’s presentation exists in mice’s memory30; however, this was not evident in THRSP OE mice as they did not prefer the novel object, which can then be an indication of inattention. Given the similarity of findings in NORT ...
The cell surface molecule syndecan-3 (SDC-3), a heparin sulfateproteoglycan, is reported to bind AgRP and facilitate signaling at the MC4R (Reizes et al., 2001). However, the mechanism of action of SDC-3 on metabolic control has been questioned as this proteoglycan does not bind to cleave...
However, two color tests are available for the identification of sulfasalazine, 5-[[p-(2-pyridylsulfamoyl)-phenyl]azo]salicylic acid [16]. This structurally related compound gives a orange-brown color when 1% w/v copper sulfate solution is added dropwise to a solution of the compound dissolved...
artery disease, isoproterenol can precipitatemyocardial ischemia. The main indication for isoproterenol is the treatment of symptomatic bradycardia or heart block, but its use is limited by the development of arrhythmias, hypotension, and metabolic disturbances. The usual dose is 0.01 to 0.05 μg/kg/...
sulfate, Kamamicin-sulfate, Neomycin-sulfate, Netimicin-sulfate and Paromomycin-sulfate, reliable information about stoichiometry with regards to sulfate is difficult to obtain. Accordingly these sulfate salts have not been further assessed. For oral administration the following sulfate salts are listed ...
mitochondria of liver cells, but only to a minute extent in serum. Since it does not occur to a significant extent in serum, kidney, brain, etc., and only 1% or 2% of the hepatic concentration occurs in small intestine, its presence in serum is a specific indication of damage to liver...
In rats, ICV-administered NOP does not induce place preference or aversion, an indication that the peptide lacks intrinsic motivational properties. Most significantly, however, NOP was later shown to block morphine-induced place preference in rats, an effect that turned out to generalize to ...
which is primarily a function of the degree of normal tension (tonus) of thesmooth muscle cellsin the walls of the arterioles. If this tonus increases above the normal range for extended periods of time, hypertension (high blood pressure) will result. This tonus is under the control of the...