The sample space is comprised of eight equally likely outcomes S={HHH,HHT,HTH,THH,TTH,THT,HTT,TTT}. Let X = the number of heads observed on any single trial of this experiment. X is a random variable. It can take on one of four values; 0, 1, 2, or 3. The probability that X...
In general, we will use a Holm-adjusted modified Bonferroni method or the false discovery rate method [33] to control experiment-wise error rates, both of which are more powerful than the Bonferroni methods. Interim analyses {21b} There will not be any interim analysis on this project. ...
One gene therapy employs an adeno-associated virus (AAV) as a vector to deliver to the gene neurturin which has been found to restore cells damaged in Parkinson’s patients and protect them from further degeneration. The first FDA-approved gene therapy experiment in the United States occurred ...
Thus, tossing a fair coin and obtaining heads corresponds to 1 bit of information, because there are just two alternatives; throwing a fair die yields log2(6) ≈ 2.59 bits of information, because there are six equally likely alternatives (H decreases if some of the outcomes are more likely ...
aA flowchart of the experiment. C57BL/6 mice were pretreated with anti-IFNAR1 monoclonal antibody MAR1-5A3 (300 µg/mouse) plus control rIgG (n = 10, 100 µg/mouse) or an LDLR blocking antibody (R004) (n = 7, 100 µg/mouse) intraperitoneally 24 h before in...
We carried out an experiment to test whether the sample size of time series has any effect on the relative performance of the estimation methods. In this specific analysis, we focus on a subset of 90 time series (out of the 174 ones) with at least 1000 observations. Further, we truncated...
which are performed using 8-min scans that range from 2θ = 10° to 100°. The XRD sample holders must be cleaned manually when the lab has depleted its stock. Precursor powders should also be refilled or replaced, when necessary, although this can be performed without stopping the wor...
There are several meta-analyses of randomized controlled trials (RCTs) demonstrating the benefits of virtual reality (VR) training as an intervention for motor performance, activity of daily living (ADL) and quality of life (QoL) outcomes in patients with Parkinson's disease (PD). However, the...
Consideration of systematicity and scope of a putative bias consequently necessitates a clear distinction between the different component processes that go into the formation of a judgment and its subsequent report (whether in an experiment or in the real world).Figure 2.4distinguishes the three main...
“relevant alternatives” toG. In particular cases, this partition will be specified by the experiment an agent is consideringGas an outcome to, or the set of alternative hypotheses under consideration, or some other contextual factor. Thus, we must think of conditional degree of beliefas a ...