(g) Hydroxymethylation of a methyl group on pyrimidines can be done using paraformaldehyde: for example, 4-methylpyrimidine gives (at 150 °C) 2-(pyrimidin-4′-yl)ethanol (155) 〈61JPR(12)206〉. (h) Methyl groups can react with alkylmetals and the resulting complex can undergo further re...
4.21.1.1.13 From cyanamides Cyanamide and monosubstituted cyanamides (52) react with a fourfold excess of an activated methylene compound such as a β-diketone, β-keto ester, β-diester, β-nitro ketone, or β-nitro ester in the presence of 1–5 mol% nickel acetylacetonate to give ketene...
Synthesis of amine–borane analog of butane, H3NBH2NH2BH3. The 11B NMR spectrum of the amidodiborane shows a single chemical shift at −27.0 ppm. The molecular structure of this compound was determined by a single-crystal diffraction on its 18-crown-6-ether adduct, since NH2B2H5 itself ...
Matrix isolation work and IR spectroscopy have identified the amine adducts TiF4(NH3) and TiF4(NMe3) at low temperature.29 Winter and co-workers have prepared TiCl4(NH3)2, and have used it as a single-source precursor for the deposition of TiN films.30 The reaction of TiCl4 with SbCl5...
In compounds with a general structure [Aryl–SO2–NH–Aryl], a homolytic cleavage of the S–N bond results in the loss of the dioxo(phenyl)-λ6-sulfanyl radical (C6H5O2S•; 141.0010 Da) or alternatives due to substitution, e.g., 2,6-difluorophenyl)(dioxo)-λ6-sulfanyl radical (C...
In the final step, the nucleophilic bromide ion reacts with the positive electrophilic tertiary carbocation to give the alkyl halide product. HINT 4.2 In rearrangement reactions, the method of numbering both the starting material and the product, introduced in Chapter 2, can be very helpful. ...
The reduced FAD then transfers to the monooxygenase component, where it reacts with molecular oxygen—similarly to the reduced FAD in the case of BVMO—allowing subsequent reaction with the alkene substrate via nucleophilic attack of the C(4a)-peroxyflavin intermediate [98]. Styrene monooxygenase-...
In general, the higher the polymer’s cohesive energy density, the more difficult it is for the polymer chains to allow molecule permeation. Chitin and chitosan contain the major hydroxyl group (CED: 220 cal/cm3) and amine group (CED: 180 cal/cm3) in the polymer pyranose backbone. These ...
The luminol in alkaline solution reacts with NO2 to produce intensive CL centred on 425 nm. The detector cell itself is a 15 cm × 8 cm × 2 cm rectangular block, with inlets and outlets for the carrier gas and luminol flows. The reaction cell contains a fabric wick that is wetted ...
4.73, 4.74, in which Fe3 + reacts with H2O and H2O2 [7]. Additionally, to reduce problems related to the separation of iron ions that persist after treatment, and thus expand the possible operating pH range, iron ions are added to the solution as a heterogeneous catalyst. In the ...