As a result of extensive research in order to creating a compound having [MEANS FOR SOLVING PROBLEMS] the S1P3 antagonist activity, the general formula (1) [Equation (1), R is substituted with a fluorine atom 1 or 2 X, and an alkyl group having 1 to 6 carbon atoms which may have a...
A solid, intimately admixed composition comprising a thermoplastic, physiologically-inert polymer soluble in body fluids, and an effective amount of a suitable medicament. The composition is suitable for introduction into a body cavity, therein to be slowly dissolved by body fluids and release thereby...
PhaseII. The purpose of these therapeutic pilot studies is to determine activity andto assess the short-term safety of the active ingredient in patients sufferingfrom a disease or condition for which it is intended. The trials are performedin a limited number of subjects and are often, at a ...
In summary, understanding the influence of human genome heterogeneity and gut microbiota spectrum diversity on IVDR is a key component in developing and improving precision medicine while minimizing ADRs.59In addition, modeling changes in gut microbiota will help to understand xenobiotic metabolism, thereb...
The term ‘active ingredient’ is frequently used to refer to the element within a pharmacologic intervention (PI) that is responsible for its therapeutic action. In contrast with PIs, non-pharmacologic interventions (NPIs) are usually complex, containing several interacting components that are all ...
This mini-review highlights the latest advances in the chemistry and biology of Pluronic[registered sign] triblock copolymers. We focus on their applications in medicine, as drug delivery carriers, biological response modifiers, and phar... AnasPitto-Barry,Nicolas P. E.Barry - 《Polymer Chemistry...
Although synthetic and semisynthetic organic substances have achieved a substantial share in pharmaceutical applications, plant-derived substances still remain a vital ingredient in modern medicine. As estimated 25% of prescriptions contain one or more active constituents obtained from higher plants. The...
In subject area: Medicine and Dentistry The FRCs are defined as controllable physical or chemical characteristics of an excipient that affect its functionality, and they may be understood as the control parameters for a specific use of an excipient. ...
"Fortunately, more recently FDA-approved treatments have greatly expanded the tools available to clinicians and their patients in forming a comprehensive migraine treatment strategy," said Nada Hindiyeh, M.D., FAHS, Director of Headache Medicine, Metrodora Institute. "These data suggest that Trudhes...
The National Institutes of Health began to organize some of their top doctors to visit China toinvestigateacupuncture and its possible functions in western medicine. With years going by, acupuncture has become popular across the world with magical effect. ...