The immunological synapse is a dynamic structure, formed between a T cell and one or more antigen-presenting cells, characterized by lipid and protein segregation, signaling compartmentalization, and bidirectional information exchange through soluble and membrane-bound transmitters. In addition, the ...
A number of modifies oligonucleotides (ONs) have been synthesized in order to evaluate their roles and functions in cell signaling. Information about the details of the experimentation procedure as well as the results of the study has been discussed....
Expressions of Rictor and Phospho-Ser473-Akt were analysed by IHC. Two Rictor antibodies from different companies (Bethyl and Cell Signaling) were applied. High expression of Rictor was detected in 14 (14/37) and 12 (12/37) cases with Bethyl and Cell Signaling antibodies, respectively. High ...
MilliplexMAP Cell Signaling Amplification Buffer 会员价请登录市场价￥935 原厂型号43-024A 贝雷猫货号RH168161 品牌默克密理博/Millipore 单件重量1kg 货期15天 单位:盒包装:盒库存:0 数量:盒+-1盒起订,增量1盒 累计成交0笔0条评价 商品名 贝雷猫货号 ...
Signaling strategyTargetDetection limitLinear rangeReference Enzyme-based amplification ALP-induced in situ producing AA as electron donor miRNA-319a 2.26 fM 5–3000 fM Yin et al. (2016) ALP catalytic redox cycling amplification system miRNA-21 0.26 fM 1fM-1nM Yi et al. (2019) Histostar@AuNPs...
This insight has important implications for the potential role of Lbc-type GEFs in cell contraction signaling. While low levels of active Lbc GEFs in unperturbed U2OS cells may play a role in sensing external inputs, higher levels of active Lbc GEFs may play a role in driving cell-autonomous...
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Patients with neuroblastoma characterized by these genetic characteristics often have suppressed T cell response and an overabundance of immunosuppressive cells and cytokines in the peripheral blood. This imbalance is significantly associated with poor EFS. Moreover, if these patients show an elevated levels...
(MET) in mouse Py2T cells26, our analysis identified that the expression ratio between Zeb1 and cyclin B1 can function as a hallmark for cells to undergo MET. Extending ACE to a second application, we simultaneously amplified 30 T cell receptor (TCR) signaling markers to comprehensively ...
Hence, it is possible that the pathways of cell signaling in response to DNA-damaging agents differ due to the types of DNA-damaging agents and also the stage of cell differentiation, because in colorectal cancer, it was observed that the extent of Skp2-p21/p27 degradation by β-catenin ...