英文摘要: OBJECTIVE To investigate the improvement effect mechanism of Xibining prescription (XBN) on knee osteoarthritis (KOA) model rats based on AMP-activated protein kinase(AMPK)/mammalian target of rapamycin (mTOR) signaling pathway. METHODS Totally 36 rats were randomly divided into blank group...
AMPKisthemainregulatorofcellandorganismenergybalanceꎬ coordinatesmulti~plemetabolicpathwaysꎬ balancesenergysupplyanddemandꎬ andultimatelyregulatesthegrowthofcellsandorgans.Theregulationofenergymetabolismbalanceismediatedbyanumberofrelatedsignalingpathwaysꎬ inwhichtheAMPK/ mTORsignalingpathwaytogetherconstitutea...
However, inhibitory effect of AMPK activity on appetite and AMPK downstream signaling pathway under stress has not been reported. In this study, we performed an intracerebroventricular (icv) injection of compound C, an AMPK inhibitor, in GC-treated birds to explore the regulatory mechanism on ...
Cold plasma promotes Sertoli cell proliferation via AMPK-mTOR signaling pathway ZHANG Jiao-jiao, LI Ya-qi, SHI Mei, WANG Yu-sha, TANG Yao, WANG Xian-zhong PDF 29 摘要/Abstract 摘要: 本研究旨在探讨低温等离子体对仔鸡睾丸支持细胞增殖的影响及其调控机制。结果发现,用2.4 W放电功率的低温等离子体...
Inhibitory effect of Xiangbeisan on growth of human breast cancer cells MCF-7 and MDA-MB-231 by activating AMPK/mTOR signaling pathway XIE Jinxin WANG Wenyi QUAN Xiaomin XING Haoqing JIA Zhi WANG Fei WEI Xuejiao TAN Peng WANG Zhuguo HU Zhongdong AN Chao 发布日期:2024-06-11摘要 访问统计 ...
Abstract: Objective To explore the role of extranuclear p53-mediated autophagy suppression by regulating AMPK/mTOR signaling pathway in heat stress (HS)-induced injury of mouse aortic endothelial cells (MAECs). Methods Primary cultures of MAECs were pretreated with compound C (an AMPK inhibitor),...
(P <0.05). Conclusion miR-29cmay target AMPK/ mTOR signaling pathway to regulate biological behavior of gastric cancer cells.[Key words] Stomach neoplasms; MicroRNA-29c; Cell proliferation; Invasiveness 胃癌是消化道肿瘤中最常见的恶性肿瘤,尽管目前全世界胃癌的发病率在稳步的下降,但是总体而言,胃癌的...
Effect of spinal cord neuronal apoptosis mediated by AMPK/MTOR signaling pathway in postherpetic neuralgia induced by resiniferatoxin 在线阅读 下载PDF 引用 收藏 分享 摘要 目的探讨单磷酸腺苷激活的蛋白激酶(AMPK)/哺乳动物雷帕霉素靶蛋白(MTOR)信号通路介导脊髓神经元凋亡在树脂毒素诱导的带状疱疹后神经痛(PHN...
mTOR/S6 kinase pathway contributes to astrocyte survival during ischemia[J]. J Biol Chem,2009,284(33):22067-22078. [36]Koh PO. Melatonin prevents ischemic brain injury through activation of the mTOR/p70S6 kinase signaling pathway[J]. Neurosci Lett,2008,444(1):74-78. [37]Koh PO,Cho JH...
Effect of Jiakangning Capsule on AMPK-mTOR Signaling Pathway in Graves’ Disease 引用 收藏 分享 摘要 目的观察甲亢宁胶囊对人甲状腺正常细胞Nthy-ori-3-1凋亡的影响,基于磷酸腺甙活化蛋白激酶(AMPK)-雷帕霉素靶蛋白(mTOR)信号通路探讨甲亢宁胶囊干预Graves病(GD)的影响。方法M22诱导人甲状腺滤泡上...展开更多...