免疫原 AMPK Alpha fusion protein Ag1367 种属同源性预测 宿主/亚型 Rabbit / IgG 抗体类别 Polyclonal 产品类型 Antibody 全称 protein kinase, AMP-activated, alpha 1 catalytic subunit 别名 AMPK Alpha 1, PRKAA1, AMPK 1, AMPK, Acetyl-CoA carboxylase kinase 计算分子量 63 kDa 观测分子量 64 kDa Gen...
AMPK beta 1 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular ...
Signals in many biological processes can be amplified by recruiting multiple copies of regulatory proteins to a site of action. Harnessing this principle, we have developed a protein scaffold, a repeating peptide array termed SunTag, which can recruit multiple copies of an antibody-fusion protein. W...
With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. 仅用于科研。不用于...
muscle cell sizeprotein synthesismTORAMPKmuscle hypertrophyenergy metabolismknockout miceNutrition and physical activity have profound effects on skeletal muscle metabolism and growth. Regulation of muscle mass depends on a thin balance between growth-promoting and growth-suppressing factors. Over the past ...
Full size image Next, we sought to identify the mechanism underlying rapid accumulation of AMPK activity at the lysosome. Lysosomal regulation of AMPK activity is thought to occur via a multi-protein complex which coordinates the lysosomal localization of AMPK and its upstream kinase LKB132,33. We...
(a,b) AMPK changed the conformation of cingulin protein molecules from “closed” to “open”. (c) The conformation of the dephosphomimetic cingulin mutant was not changed by AMPK. Bar, 200 nm. Full size image AMPK phosphorylation of cingulin’s head domain regulates the binding of ...
Target Protein:phospho-AMPK alpha 1 (Thr183) + AMPK alpha 2 (Thr172) IR:Immunogen Range:LR(p-T)SC Clonality:Polyclonal Isotype:IgG Entrez Gene:5562 Swiss Prot:Q13131 Source:KLH conjugated Synthesised phosphopeptide derived from human AMPK alpha 1 around the phosphorylation site of Thr183:LR(...
目的:探究腺苷酸活化蛋白激酶(AMP-activated protein kinase, AMPK)的 激动剂抑制白色脂肪组织和血管周围脂肪组织(Perivascular adipose tissue, PVAT)巨噬细胞相关炎症的作用及其相关机制。方法:采用高脂喂养建立 C57BL/6 肥胖小鼠模型,分别给予AMPK 直接激动剂A769662 及间接激动剂二 甲双胍(Metformin)干预 12 周...
Target Protein:phospho-AMPK beta 1 + AMPK beta 2 (Ser182/Ser184) IR:Immunogen Range:SS(p-S)PP Clonality:Polyclonal Isotype:IgG Entrez Gene:5564 Swiss Prot:Q9Y478 Source:KLH conjugated synthesised phosphopeptide derived from human AMPK beta 1 around the phosphorylation site of Ser182:SS(p-S...