Ampicillin, a cornerstone of modern medicine, stands as a testament to the transformative power of scientific discovery. Its introduction in the 1940s revolutionized the treatment of bacterial infections, ushering in an era of unprecedented medical progress. This remarkable antibiotic, derived fro...
Ampicillin acts by interfering directly with the biosynthesis of peptidoglycan, which constitutes the major component of the bacterial cell wall, leading to structural instability and death of bacteria. Ampicillin is a β-lactam antibiotic within the penicillin family. As a member of this family, ...
AMPICILLIN is a semisynthetic antibiotic, a member of the penicillin family of antibiotics. To extend the usefulness of the penicillins to the treatment of infections caused by gram-negative rods, the broad-spectrum penicillins (ampicillin, amoxicillin, carbenicillin, and ticarcillin) were developed....
Ampicillin is an antibiotic in the broad-spectrum penicillin group. Ampicillin differs from penicillin only by the presence of an amino group, which facilitates penetration through the outer membrane of some gram-negative bacteria. Ampicillin acts by
Derivative Type:L(+)-Form Properties:Crystals, dec at about 205°. [a]D20+209° (c = 0.2 in water). Less active as an antibiotic thanD(-)-form. Optical Rotation:[a]D20+209° (c = 0.2 in water) Therap-Cat:Antibacterial.
Synopsis Sulbactam is a semisynthetic 尾 -lactamase inhibitor which when combined with certain 尾-lactam antibacterials extends their activity against bacteria that are normally resistant to the antibiotic due to production of 尾 -lactamases. In combination with ampicillin 1 it extends the antibacterial ...
Use of Ampicillin Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria. Properties Articles1074 Spectrum Contents: Names Biological Activity Chemical & Physical Properties Toxicological Info Safety Info Synthetic Route Precursor & Downstream ...
An antibiotic related to penicillin that is used to treat a wide variety of infections in the body caused by bacteria. DrugBank ID DB00415 Type Small Molecule US Approved YES Other Approved YES Patents 0 Indicated Conditions 19 Clinical Trials Phase 0 1 Phase 1 2 Phase 2 12 Phase 3 18 Pha...
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The minimal inhibitory concentration (MIC) was the smallest concentration of antibiotic(s) preventing a visible button of growth after incubation at 37C for 18h. Synergy, determined by isobolograms made from MICs, occurred against 6 of 13 ampicillin-susceptible and against 5 of 8 ampicillin-...