Crossreactivityis regular with ampicillin and can occur withother penicillins. 2.7 Odor Odorless or has a faint odor characteristic of the penicillins 2.8 pKa 2.5 (COOH)(at 25℃) 2.9 Water Solubility H2O: 0.1-1 g/100 mL at 21 oC;NH4OH 1 M: 50?mg/mL, clear, colorless 2.10 Spectral ...
Therefore, the thiazolidine ring-epitope acts in broad cross-reaction among β-lactams, and the acyl side chain acts only in the cross-reactivity between penam and cephem, which have a similar acyl side chain. 展开 DOI: 10.1093/jac/28.3.357 年份: 1991 ...
Crossreactivity is regular with ampicillin and can occur with other penicillins. Safety Profile Moderately toxic by intraperitoneal route. Human systemic effects by ingestion: hypermotility, diarrhea, and other gastrointestinal changes. Questionable carcinogen. When heated to decomposition it emits very ...
Contact allergensAmpicillin caused contact dermatitis in a nurse also sensitized to amoxicillin (with tolerance to oral phenoxymethylpenicillin) and in a pharmaceutical factory worker. Systemic drug reactions are common. Crossreactivity is regular with ampicillin and can occur with other penicillins. ...
Polyclonal antibodies were obtained against ampicillin conjugated with bovine serum albumin; the conjugate was synthesized by direct condensation using carbodiimide. The antibodies were specific for ampicillin and exhibited low cross-reactivity to other penicillins (azlocillin, 17%; penicillin G, 10%; ...
antibodieswithspeci®cityforintactampicillinwereselectedbyphage displayandcharacterized.TheantibodyscFvfragmentaL2bindsto intactampicillinandshowsnodetectablecross-reactivitywithhydro- lyzedampicillin.WedeterminedtheX-raystructuresoftwocrystal formsofw.t.aL2,whichdiffermainlyintheside-chainconformationof ...
The structure explains the specificity of the antibody for intact ampicillin and the degree of cross-reactivity of aL2 with a wide variety of ampicillin analogs. This antibody system will be very useful as a diagnostic reagent for antibiotics use and abuse, as a model for the effect of ...
PenicillinSulfonamide antibioticThere is a theoretical concern, unconfirmed by population-based challenge data, that clinically significant, immunologically mediated hypersensitivity occurs among 尾-lactams sharing side chains.#To determine the population-based allergy incidence associated with the use of 尾-...
Contact allergensAmpicillin caused contact dermatitis in a nurse also sensitized to amoxicillin (with tolerance to oral phenoxymethylpenicillin) and in a pharmaceutical factory worker. Systemic drug reactions are common. Crossreactivity is regular with ampicillin and can occur with other penicillins. ...
Crossreactivity is regular with ampicillin and can occur with other penicillins. Safety Profile Moderately toxic by intraperitoneal route. Human systemic effects by ingestion: hypermotility, diarrhea, and other gastrointestinal changes. Questionable carcinogen. When heated to decomposition it emits very ...