drug of abuse,street drug- a drug that is taken for nonmedicinal reasons (usually for mind-altering effects); drug abuse can lead to physical and mental damage and (with some substances) dependence and addiction deoxyephedrine,meth,methamphetamine,methamphetamine hydrochloride,Methedrine,shabu,chicken...
amphetamine is used as a drug of abuse and as a stimulant for recreational purposes. There have been 136 studies of amphetamine in clinical trials (Table2). These studies make it obvious that research is ongoing on other indications, such as...
Amphetamine is the most basic member of this class of drugs and has a very high binding affinity for the DAT, evoking a large release of dopamine through this transporter. Adding a methyl group to the amine of amphetamine produces METH, which has a roughly equivalent affinity for the DAT ...
Today, amphetamines are used legally as a prescription drug for the treatment of narcolepsy, ADHD, obesity, chronic fatigue syndrome and depression. It is also used to improve brain development. Illegally produced amphetamine is sold for its stimulant properties. ...
P. E. Gay is currently Visit- ing Associate Professor of Psychiatry. University of Utah School of Medicine. Method Subjects. The subjects were 12 male Holtzman rats (331- 620 g), selected from a larger population of approximately 160 because they killed mice on a I-h pretest. The prey ...
. The modern formulation of amphetamine for ADHD treatment is a combination of racemic amphetamine and d-amphetamine (e.g. Adderall). Also in the amphetamine class is methamphetamine, or “meth,” the N-methylated form of the drug. Both Adderall and meth are commonly abused to...
Statistical interaction between genotype and treatment suggests that this is distinguishable from baseline reduction in activity in Drd2 À / À mice. This finding is consistent with evidence showing reduced acute stimulatory effects of methamphe- tamine in Drd2 À / À mice (Kelly et al, ...
Thus, it is important to understand functional adaptations of D2 autoreceptors in response to repeated drug exposure, which may be a mechanism under- lying susceptibility to drug addiction. D2 receptors are also located postsynaptically on DA neurons in the striatum. Reduced postsynaptic D2 ...
drug of abuse,street drug- a drug that is taken for nonmedicinal reasons (usually for mind-altering effects); drug abuse can lead to physical and mental damage and (with some substances) dependence and addiction deoxyephedrine,meth,methamphetamine,methamphetamine hydrochloride,Methedrine,shabu,chicken...
It discusses the conversion of MA and AP enantiomers and DMSG to trifluoroacetic acid derivatives. The article shows that discrimination of MA abusers from SG users is possible by comparing optical isomers of MA and AP, the existence of DMSG and/or SG, and the concentration ratio of AP to ...