Severe infection: 500 mg orally every 8 hours or 875 mg every 12 hours Uses: Usual Adult Dose for Urinary Tract Infection Immediate-release: Mild to moderate infection: 250 mg orally every 8 hours or 500 mg every 12 hours Severe infection: 500 mg orally every 8 hours or 875 mg every 12...
Severe (CrCl 10-30 mL/min): 250-500 mg q12hr, depending on severity of infection; should not receive 875 mg Severe (CrCl <10 mL/min) or patients on hemodialysis: 250-500 mg q24hr, depending on severity of infection; patients on hemodialysis should receive an additional dose both during...
Severely impaired patients with a glomerular filtration rate of < 30 mL/min. should not receive a 875-mg dose. Patients with a glomerular filtration rate of 10 to 30 mL/min should receive 500 mg or 250 mg every 12 hours, depending on the severity of the infection. ...
Severely impaired patients with a glomerular filtration rate of < 30 mL/min. should not receive a 875-mg dose. Patients with a glomerular filtration rate of 10 to 30 mL/min should receive 500 mg or 250 mg every 12 hours, depending on the severity of the infection. ...
Patients with impaired renal function do not generally require a reduction in dose unless the impairment is severe. Severely impaired patients with a glomerular filtration rate of < 30 mL/min should not receive a 875 mg dose. Patients with a glomerular filtration rate of 10 to 30 mL/min shoul...
Severe 875 mg every12 hours or 500 mg every 8 hours 45 mg/kg/day in divided doses every 12 hours or 40 mg/kg/day in divided doses every 8 hours Gonorrhea Acute, uncomplicated ano-genital and urethral infections in males and females 3 grams as single oral dose Prepu...
For the treatment of severe genitourinary infections, the recommended dose for adults is 875mg every 12 hours or 500mg every 8 hours. The usual dose for children (> 3 months) is 45mg/kg every 12 hours or 40mg/kg every 8 hours.
Renal impairment:Patients with impaired renal function typically do not necessitate a dose reduction unless the impairment is severe. However, individuals with severe renal impairment, defined by a glomerular filtration rate of <30 mL/min, should not receive an 875-mg amoxicillin dose. Patients with...
Amoxicillin dose for renal impairment patients: Renal impairment patients with glomerular filtration rate < 30 mL/min should not receive an 875 mg dose. Instead, they are administered with 500 mg or 250 mg every 12 hours based on the severity of the condition. Renal impairment patients with glo...
4 A 875mg dose of oral amoxicillin reaches a Cmax 11.21±3.42mg/L with a Tmax 1.52±0.40h and an AUC of 55.04±12.68mg*h/L.4 Volume of distribution The central volume of distribution of amoxicillin is 27.7L.4 Protein binding Amoxicillin is 17% protein bound in serum.3 Metabolism ...