The woman, who had a history of depression, hypertension and hypothyroidism, was taking nifedipine, aspirin and metoprolol. While travelling, she ran out of her nifedipine tablets and self-medicated with her husband's amlodipine. She started taking oral amlodipine 10mg twice a day. Ten days ...
q.d., once a day; b.i.d., twice a day. Table 4.Structure–activity relationship of some dihydropyridines DrugR1R2R3R4R5Advantages NifedipineCO2CH3CO2CH3HNO2CH3First in class FelodipineCO2CH3CO2C2H5ClClCH3Vasoselective NitrendipineCO2CH3CO2C2H5NO2HCH3Vasoselective ...
"Days supply" is defined as the number of days that a prescription should last. For example, a prescription of 60 tablets that is taken twice daily has a day supply of 30 days. Related Drugs Drug NameTotal Prescriptions (2022) Amlodipine(this drug)70,766,211 ...
For the mouse, the highest dose was, on a mg/m2 basis, similar to the maximum recommended human dose of 10 mg amlodipine/day.3 For the rat, the highest dose was, on a mg/m2 basis, about twice the maximum recommended human dose. 3 Mutagenicity studies conducted with amlodipine maleate...
There was a higher incidence of persistent hepatic transaminase elevations (≥ 3 x ULN twice within 4–10 days) in the atorvastatin group (0.9%) compared to placebo (0.1%). Elevations of CK (> 10 x ULN) were rare, but were higher in the atorvastatin group (0.1%) compared to placebo ...
On day 11, the amlodipine dosage was increased to 5mg twice daily and then simplified to 10mg at night 3 days later. She was discharged on day 17 receiving warfarin, amlodipine and atenolol. Three days late ... 展开 DOI: 10.2165/00128415-200711650-00016 年份: 2007 ...
The very long half-life of amlodipine, goodtolerability, and virtual absence of drug interactions (exception: high-dose simvastatin) makes it an effective once-a-day antianginal and antihypertensive agent, setting it apart from agents that are either twice or thrice daily.Side effectsare few;ankl...
For the mouse, the highest dose was, on a mg/m² basis, similar to the maximum recommended human dose of 10 mg amlodipine/day.1 For the rat, the highest dose was, on a mg/m² basis, about twice the maximum recommended human dose.1 Mutagenicity studies conducted with amlodipine ...
(n=2,366) for a median folow-up of 4.9 years, there was a higher incidence of persistent hepatic transaminase elevations (≥ 3 × ULN twice within 4–10 days) in the atorvastatin group (0.9%) compared to placebo (0.1%). Elevations of CK (>10 × ULN) were rare, but were higher ...
(n=2,366) for a median folow-up of 4.9 years, there was a higher incidence of persistent hepatic transaminase elevations (≥ 3 × ULN twice within 4–10 days) in the atorvastatin group (0.9%) compared to placebo (0.1%). Elevations of CK (>10 × ULN) were rare, but were higher ...