A single 100 mg dose of sildenafil in subjects withessentialhypertension had no effect on the pharmacokinetic parameters of amlodipine. When amlodipine and sildenafil were used in combination, each agent independently exerted its own blood pressure lowering effect. ...
Figure 1 Analysis of pupillary light reflex parameters using pupillometry. D1, initial pupil diameter; D2, minimal pupil diameter; VC, maximal velocity of pupil constriction (velocity of miosis); VD, maximal velocity of pupil re-dilation (velocity of mydriasis). pupillary function. On the ...
administered in combination with beta-blockers to patients with either hypertension or angina, no adverse effects of electrocardiographic parameters were observed. In clinical trials with angina patients alone, amlodipine therapy did not alter electrocardiographic intervals or produce higher degrees of AV ...
Differential pulse voltammetryCyclic voltammetryPencil graphite electrodeA reproducible and sensitive voltammetric procedure has been developed for the determination of amlodipine (AML) by using pencil graphite electrode (PGE) as working electrode. The experimental parameters, such as concentration, pH, ...
The pulse wave velocity (PWV) and some hemodynamic parameters have been associated with this outcome [2,3]. Losartan, as well as amlodipine, have shown benefits on hemodynamic parameters [4,5] however, it is unknown if losartan/amlodipine combination is better than losartan as a monotherapy. ...
2A.06: COMPARATIVE STUDY OF THE EFFICACY OF OLMESARTAN/AMLODIPINE VERSUS PERINDOPRIL/AMLODIPINE IN PERIPHERAL AND CENTRAL BP PARAMETERS AFTER MISSED DOSE I... 2A.06: COMPARATIVE STUDY OF THE EFFICACY OF OLMESARTAN/AMLODIPINE VERSUS PERINDOPRIL/AMLODIPINE IN PERIPHERAL AND CENTRAL BP PARAMETERS AFTER MIS...
amlodipine on central blood pressure (CBP), left ventricular (LV) mass index (LVMI), LV dia- stolic function (e′ velocity, E/e′ ratio, E/A ratio) and arterial stiffness (brachial-ankle pulse wave velocity [baPWV] and augmentation index normalized for a heart rate of 75 bpm [AIx]...
Parameters of vascular endothelial function and inflammation are displayed in Figure 4. Both hs-CRP and vWF were significantly lower with NIF treatment than with AML treatment (P¼0.0382 and P¼0.0263, respectively). DISCUSSION Although there is abundant evidence that long-acting Ca antagonists ...
Differential pulse voltammograms were recorded in the specified potential range by using the following optimized parameters: step potential = 5 mV, modulation amplitude = 50 mV and scan rate = 50 mV s−1. All electrochemical measurements were performed in triplicate and the mean values were ...
Sildenafil:A single 100 mg dose of sildenafil in subjects with essential hypertension had no effect on the pharmacokinetic parameters of amlodipine. When amlodipine and sildenafil were used in combination, each agent independently exerted its own blood pressure lowering effect. ...