Improved Survival Rates Among Acute Myeloid Leukemia (AML) Patients 65 to 74 Years: Population-Based Estimates Over Three Decades,Mya S TheinAhmedin JemalMaria R. BaerWilliam B ErshlerJerome W Yates
参考文献：Slezak, A. J., et al. (2024). Cysteine-binding adjuvant enhances survival and promotes immune function in a murine model of acute myeloid leukemia. Blood Advances. doi.org/10.1182/bloodadvances.2023012529.
POSTER: AML-068 Survival Differences in Patients With Acute Myeloid Leukemia (AML) Treated With Oral Azacitidine (Oral-AZA) as Maintenance and Those Eligib... AML-068- Survival Differences in Patients With Acute Myeloid Leukemia (AML) Treated With Oral Azacitidine (Oral-AZA) as Maintenance and ...
In younger adults with newly diagnosed acute myeloid leukemia (AML), anthracycline dose intensification during induction may improve complete remission (CR) rates; however, an improvement in overall survival (OS) in a randomized trial ha... HF Fernandez,Z Sun,MR Litzow,... - 《Journal of Clini...
通过对部分家系口腔黏膜样本的联合基因序列分析,证实部分DDX11突变为胚系突变(图3),这对白血病患者精准诊疗及全球应用最广泛的半相合干细胞移植实施“北京方案”中优选供者,以提高患者生存期,具有重要的意义。该研究结果于2023.11.22在线发表于Leukemia(Q1)。
Acute myeloid leukemia (AML) is a serious, life-threatening, and hardly curable hematological malignancy that affects the myeloid cell progenies and challenges patients of all ages but mostly occurs in adults. Although several therapies are available inc
The effective treatment of acute myeloid leukemia (AML) is very challenging. Due to the immense heterogeneity of this disease, treating it using a “one size fits all” approach is ineffective and only benefits a subset of patients. Instead, there is a shift towards more personalized treatment ...
thereby liberating cytosolic NF-κB.14 As NF-kB promotes TNF-α expression, a positive-feedback loop is created between NF-κB and TNF-α, promoting cell survival and progression of the leukemia (Figure 1).14 This NF-κB/TNF-α feedback loop – and the survival of LSCs – is highly de...
Results from a large cohort of older patients with acute myeloid leukemia (AML) from The Beat AML study (NCT03013998) demonstrated that intensive chemotherapy yields the highest median overall survival (OS) for this patient population, showing the importance of pretreatment factors, such as age, pe...
[1] Arthur C, Jeffrey A, Yip E, Katsioulas V, et al. Prolonged administration of low-dose cytarabine and thioguanine in elderly patients with acute myeloid leukaemia (AML) achieves high complete remission rates and prolonged survival. Leuk Lymphoma. 2020 Apr;61(4):831-839. ...