Kantarjian HM, Kadia TM, DiNardo CD, et al. Acute myeloid leukemia: treatment and research outlook for 2021 and the MD Anderson approach. Cancer. 2021;127(8):1186–1207. doi: 10.1002/cncr.33477. Epub 2021 Mar 18. LeBlanc TW, Areej El...
MD Anderson癌症中心Xu Jie等人在Clin. Lab. Med. 12月份这期的文章《How Do We Use Multicolor Flow Cytometry to Detect Minimal Residual Disease in Acute Myeloid Leukemia?》给了我们很好的总结。 1、方案 8色方案,4管(不得不感叹国外的抗体像不要钱似的用) 2、设门 (1)每管分析均先排除碎片和粘连体,...
参考文献 Phase II study of cladribine, idarubicin, and ara-C (CLIA) with or without sorafenib as initial therapy for patients with acute myeloid leukemia. Am J Hematol. 2023 Nov;98(11):1711-1720. doi: 10.1002/ajh.270...
Naval DaverMD Anderson Cancer CenterAdv Exp Med Bioladvances in experimental medicine & biologyHarnessing the immune system against leukemia:monoclonal antibodies and checkpoint strategies for AML. Masarova L,Kantarjian H,Garcia-Mannero G,et al. Advances in Experimental Medicine and Biology . 2017...
美国MD Anderson癌症中心Musa Yilmaz教授及Naval Daver教授在同期Lancet Haematology发表评述,认为FLT3-ITD阳性AML患者allo-HSCT后使用索拉非尼维持治疗,不仅复发风险降低,总体存活率也有所提高,该研究成果提供了令人信服的证据。 作者介绍 通讯作者 刘启发 南方医科大学血液病研究院院长、血液病研究所所长;南方医院血液科...
引用:Sergej Konoplev, Carlos E Bueso-Ramos.Advances in the pathologic diagnosis and biology of acute myeloid leukemia. Annals of Diagnostic Pathology 10 (2006) 39– 65. 参考文献: 1.James W. Vardiman, Jüergen Thiele, Daniel A. Arber,et al. The 2008 Revision of the WHO Classification of My...
Balanced chromosomal rearrangements define distinct entities in acute myeloid leukemia (AML). Here, we present 13 AML cases with t(8;16)(p11;p13) with observed low incidence (13/6124 patients), but more frequent presentation in therapy-related AML than in de novo AML (7/438 versus 6/5686,...
OPEN Citation: Blood Cancer Journal (2016) 6, e503; doi:10.1038/bcj.2016.112 www.nature.com/bcj REVIEW The role of the proteasome in AML CM Csizmar1, D-H Kim2 and Z Sachs3 Acute myeloid leukemia (AML) is deadly hematologic malignancy. Despite a well-characterized genetic and molecular ...
【Key words】 Cladribine Venetoclax Elderly Acute myeloid leukemia ·540· 老年急性髓系白血病(acute myeloid leukemia, AML)患者临床治疗存在困境,多数合并不良高危 基因突变,且多合并基础疾病,体能状态较差,初次 诱导治疗风险较大.目前临床老年AML患者诱导治 疗需结合患者MICM分型,预后分层,基础疾病合并 症,体能...
Until recently, acute myeloid leukemia (AML) patients used to have limited treatment options, depending solely on cytarabine + anthracycline (7 + 3) intensive chemotherapy and hypomethylating agents. Allogeneic stem cell transplantation (Allo