Plasma prolactin concentrations are increased, particularly in the early weeks of amisulpride therapy. Two absorption peaks are demonstrated after a single oral dose of amisulpride 50mg in healthy volunteers; peak plasma concentrations of 42 and 56 g/L were recorded at hours 1 and 4. The absolute...
Barhemsys may result in an increase in serum prolactin levels, which may lead to a reversible increase in maternal milk production. In a clinical trial, serum prolactin concentrations in females (n=112) increased from a mean of 10 ng/mL at baseline to 32 ng/mL after Barhemsys treatment ...
Common(1% to 10%): Reversible increase in plasma prolactin levels Rare(0.01% to 0.1%): Syndrome of inappropriate antidiuretic hormone secretion (SIADH) Frequency not reported: Gynecomastia[Ref] Female patients given a single, 5 to 10 mg IV dose over 1 to 2 minutes had serum prolactin levels...
amisulpride affects dopaminergic control of plasma hormone levels. Amisulpride produced a significant increase in daytime and nocturnal prolactin levels in healthy volunteers. Daytime, but not nocturnal, thyroid-stimulating hormone
Common adverse reactions (≥2%) in patients receiving amisulpride for prevention of PONV: increased blood prolactin concentrations, chills, hypokalemia, procedural hypotension, and abdominal distension.Common adverse reactions (≥2%) in patients receiving amisulpride for treatment of PONV: infusion site ...
Amisulpride increased prolactin levels in volunteers. Consistent with its lack of effects on the α-adrenergic and cholinergic system, amisulpride produced minor or no neurocardiac effects. Pharmacokinetic Properties After sin 展开 关键词: Schizophrenia Haloperidol Risperidone Negative Symptom Brief Psychiatric...
Another similarity to risperidone is the risk of elevated prolactin. Amisulpride's superiority in acute psychosis for global and negative symptoms when compared with conventional antipsychotics must be qualified. These studies have routinely used conventional antipsychotic doses equivalent to 12 mg/day of...
Plasma prolactin concentrations are increased, particularly in the early weeks of amisulpride therapy. Two absorption peaks are demonstrated after a single oral dose of amisulpride 50mg in healthy volunteers; peak plasma concentrations of 42 and 56 g/L were recorded at hours 1 and 4. The absolute...
Amisulpride: Galactorrhoea secondary to hyperprolactinaemia, and other symptoms: 3 case reports
Amisulpride, a unique atypical antipsychotic, significantly increases prolactin secretion during schizophrenia treatment, resulting in adverse effects that reduce patient quality of life and treatment adherence. Aripiprazole, a partial dopamine D2 receptor agonist, reduces prolactin elevation induced by ...