and Piepersburg, W., 1985, Purification and characterization of a plasmid-encoded aminoglycoside-(3)-N-acetyltransferase IV from Escherichia coli , FEBS Letts 185:43–46.BRAU B, PIEPERSBERG W. Purification and characterization of a plasmid-encoded aminoglycoside-(3)-N-acetyhransferase Ⅳ from ...
AAC, aminoglycoside acetyltransferase; ANT, aminoglycoside nucleotidyltransferase; APH, aminoglycoside phosphotransferase. A Full color version of this figure is available at Journal of Antibiotics online. The Journal of Antibiotics Destination of aminoglycoside antibiotics Y Takahashi and M Igarashi 9 Figure...
Figure 2.Chemical structure of the bisubstrate analog inhibitor of gentamycin acetyltransferase. More recently, the Auclair group has reported a more extensive investigation of bisubstrate analog inhibitors toward aminoglycoside 6′-N-acetyltransferase (AAC(6′)-Ii) fromEnterococcus faecium. AAC(6′)-Ii...
A.M. (1991) Nucleotide sequence of the aacC3 gene, a gentamicin resistance determinant encoding aminoglycoside-(3)-N-acetyltransferase ... JS Vliegenthart,PA Ketelaar-Van Gaalen,dKJA Van - 《Antimicrobial Agents & Chemotherapy》 被引量: 88发表: 1989年 Genes for gentamicin-(3)-N-acetyl-...
The aminoglycoside 3-N-acetyltransferase AAC(3)-IV from Escherichia coli exhibits a very broad aminoglycoside specificity, causing resistance to a large number of aminoglycosides, including the atypical veterinary antibiotic, apramycin. We report here on the characterization of the substrate specificity ...
() Citation Context ...origin were resistant to apramycin by synthesis of a plasmid-mediated 3-N-aminoglycoside acetyltransferase type IV, which also confers resistance to gentamicin (4). Following spread in animal strains =-=(5)-=-, the plasmid was later found in clinical isolates from ...
Crystal structure of a GCN5-related N-acetyltransferase: Serratia marcescens aminoglycoside 3-N-acetyltransferase. Cell 1998, 94, 439–449. [CrossRef] 21. Vetting, M.W.; Hegde, S.; Javid-Majd, F.; Blanchard, J.S.; Roderick, S.L. Aminoglycoside 2 -N-acetyltrasferase from Mycobacterium ...