aminoacyl-trna biosynthesis相关的代谢通路aminoacyl-trna biosynthesis相关的代谢通路 aminoacyl-tRNA(tRNA的氨酸结合核糖核酸)是细胞内的重要分子,它在蛋白质合成中起着至关重要的角色。其通过一个复杂的生物合成途径进行合成,涉及多个酶催化的反应。本文将一步一步地回答有关aminoacyl-tRNA合成的相关问题,详尽地介绍其...
aminoacyl-tRNA biosynthesis-htmlKaren, Fugate
Aminoacyl-tRNA biosynthesis Aminoacyl-tRNAsynthetases (ARSs) are essential for the first step inprotein synthesis. It has been reported that defects in ARS functions may contribute to several diseases such as cancer[58]. Ametabolomicapproach forleukemia cellstreated with rosemary PCs showed an increase...
The perturbation of aminoacyl-tRNA biosynthesis could be attributed to an increased demand for antioxidative enzymes, stress proteins, or DNA repair enzymes (Guo and Schimmel, 2013; Moore et al., 2016). Show abstract Impact of imidacloprid exposure on the biochemical responses, transcriptome, gut ...
Based on the MetaboAnalyst results, the most impacted pathways after bariatric interventions are aminoacyl-tRNA biosynthesis; glycine, serine, and threonine metabolism; nitrogen metabolism; phenylalanine metabolism; cysteine and methionine metabolism; TCA cycle (citrate cycle); taurine and hypotaurine metaboli...
V. et al. Production of new cladosporin analogues by reconstitution of the polyketide synthases responsible for the biosynthesis of this antimalarial agent. Angew. Chem. Int. Ed. Engl. 55, 664–668 (2016). CAS PubMed Google Scholar Yoon, S. et al. Discovery of leucyladenylate sulfamates ...
Aminoacyl-tRNA-Synthetase(Enzym,dasdietRNAbelädt) 单语范例(未经PONS编辑处理) 英语 This enzyme participates in alanine and aspartate metabolism and aminoacyl-trna biosynthesis. en.wikipedia.org This enzyme participates in 3 metabolic pathways: lysine biosynthesis, aminoacyl-trna biosynthesis, and amyotrop...
(aaRS)areattheheartofmoderntranslation,catalyzingtheaccuratebiosynthesisofaminoacyl-tRNAs(aa-tRNAs),theimmediateprecursorsforencodedpeptides.However,thefirstcatalyststhatmadeaa-RNAsforcodedproteinsynthesisproba-blyappearedlongbeforeanyproteinaaRS,toserveapreexistingtransla-tionsystem(seebelow).Itpresentlyseemslikely...
Protein biosynthesis:translation(prokaryotic,eukaryotic) Ribosomal proteinsInitiation factor(Prokaryotic,Eukaryotic) -Elongation factor(Prokaryotic,Eukaryotic) - Release factor (Prokaryotic, Eukaryotic) - Ribosomal protein s6 Other conceptsAminoacyl tRNA synthetase-Reading frame-Start codon-Shine-Dalgarno sequence/Ko...
The specific sub-population of neurons affected in CMT sharply contrasts with the broad requirement of aaRSs for protein biosynthesis, indicating that the impact of aaRSs in peripheral nerves may not be limited to protein translation. In addition to their well characterized localization in the ...