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Amino acid homeostasis is critical for many cellular processes. It is well established that amino acids are compartmentalized using pH gradients generated between organelles and the cytoplasm; however, the dynamics of this partitioning has not been explo
Plants produce floral nectar as a reward for pollinators, which contains carbohydrates and amino acids (AAs). We designed experiments to test whether pollinators could exert selection pressure on th...
Fig. 4: Identification of amino acids with PTMs and the unnatural amino acid. Full size image The incorporation of unnatural amino acids with novel side chains into proteins introduces a new dimension to the study of protein structure and function. Previous research has involved the investigation ...
It has been shown that mothers who consume a lot of dietary fiber, omega-3 fatty acids, and polyphenols during pregnancy had a large number of bacteria of the genus Ruminococcus, those who had a lot of plant foods in their diet were associated with a higher presence of the Christensellace...
(R and R to display C alkyl group here, R and R to display the hydrogen atom or hydroxyl group, as for Y the next formula (7)[Conversion 2](7)(In formula, Me after asymmetrical hydrogenation reacting dehydroacetic amino acids, adding water the L-2- amino -4- which features that it...
The present invention concerns cyclic amino acids of formula ##STR1## substantially free from the lactam ##STR2## wherein n is an integer of from 4 to 6, a process for the preparation thereof, composi
Dietary proteins have been used for years to treat obesity. Body weight loss is beneficial when it concerns fat mass, but loss of fat free mass – esp
Branched-chain amino acids (BCAAs; leucine, isoleucine, and valine) are essential amino acids that must be acquired from the diet. To support sustained biomass accumulation, cancer cells require increased levels of nutrients such as amino acids. Indeed, cancer cells have increased BCAAs uptake17,...
Here we discovered that missense mutant p53 oncoproteins stimulate de novo serine/glycine synthesis and essential amino acids intake, promoting breast cancer growth. Mechanistically, mutant p53, unlike the wild-type counterpart, induces the expression of serine-synthesis-pathway enzymes and L-type amino...